Interdisciplinary Training Program in Muscle Biology

描述：（取自申请人的）该计划提供 为博士前和博士后提供肌肉生物学的跨学科培训 学生该计划强调骨骼，心脏， 和平滑肌18名小学教员来自4个系， 马里兰州大学医学院，巴尔的摩和2个巴尔的摩单位 马里兰州大学生物技术研究所的研究员， 工程学院，马里兰州巴尔的摩县大学。反映 这种教师背景的多样性，培训机会涵盖广泛 范围和包括：肌肉细胞骨架的分子生物学决定因素 和基质，生物物理和生理分析的功能， 单个肌肉细胞，整个肌肉和肌肉的生物力学特性 器官，以及这些方法与肌肉疾病的关系。的 教师在肌肉功能和肌肉钙控制领域的工作 细胞骨架和基质。学生将接受这些方面的培训， 各种相关领域，包括肌肉的分子和功能控制 基因表达，重点是使用几种互补技术 来处理调查中的每个问题。的主要方面 教学训练包括两个跨学科的课程，肌肉已经 由项目教师提供。 他们建议第一和第二批培养4名博士前和5名博士后 更新一年的计划，然后一个稳定的状态5前和6 第三年至第五年的博士后培训人员。进入predoctoral 学员将有生物学，化学和/或物理学背景，优秀 GRE成绩，研究经验和强有力的推荐信。传入 博士后学员将完成一个坚实的博士学位。论文，并有很强的 推荐信。该应用程序具有重大和实质性的 科学价值建议为五年期提供支助， 在预算中，与优秀的评级。

DESCRIPTION: (Taken from the applicant's) This program provides interdisciplinary training in muscle biology for pre- and postdoctoral students. The program emphasizes the functional properties of skeletal, cardiac and smooth muscle. The 18 primary faculty members are from 4 departments at the University of Maryland School of Medicine, Baltimore, and the 2 Baltimore units of the University of Maryland Biotechnology Institute, with affiliates from the College of Engineering, University of Maryland Baltimore County. Reflecting this diversity of faculty backgrounds, the training opportunities cover a wide range and include: the molecular biological determinants of muscle cytoskeleton and matrix, biophysical and physiological analysis of the function of individual muscle cells, biomechanical properties of whole muscles and muscular organs, and the relationship of each of these approaches to muscle disease. The faculty work in the areas of calcium control of muscle function and muscle cytoskeletal and matrix. The students will receive training in these and a variety of related areas, including molecular and functional control of muscle gene expression, with emphasis on the use of several complementary techniques to approach each question under investigation. The major aspects of the didactic training consists of two interdisciplinary courses on muscle already offered by program faculty. They propose 4 predoctoral and 5 postdoctoral trainees for the first and second renewal year of the program, and then a steady state of 5 pre- and 6 postdoctoral trainees in the third through fifth years. Entering predoctoral trainees will have a background in biology, chemistry and/or physics, excellent GRE scores, research experience and strong letters of recommendation. Incoming postdoctoral trainees will have completed a solid Ph.D. thesis and have strong letters of recommendation. The application has significant and substantial scientific merit. Support is recommended for the five years, with a reduction in the budget, with a rating of outstanding.