Gas Chromatograph Mass Spectrometer

描述(由申请人提供)：本提案要求为购买气相色谱/质谱仪(GC/MS)提供资金，这对印第安纳大学医学院当前和未来的人类和动物营养与新陈代谢研究项目至关重要。所要求的仪器是质谱学核心实验室的关键组成部分，自1989年以来，该实验室一直支持NIH资助的研究人员进行稳定的同位素示踪研究。目前已有13年历史的仪器已多年未生产，现在该公司已停止对该仪器的所有服务支持。取代这种GC/MS对于目前资助的3个R01项目和1个K23赠款，以及质谱学核心实验室为其他和未来研究提供分析的能力至关重要。特别是，核心实验室一直支持并继续支持对使用稳定同位素技术的新调查人员进行临床研究培训。培养新的临床研究人员是美国国立卫生研究院和印第安纳大学医学院的重要目标，而新的仪器设备将使这一目标继续下去。最后，一种新的、更有效的仪器将促进校园内其他调查人员使用实验室的能力。

DESCRIPTION (provided by applicant): The present proposal requests funding for the purchase of a gas chromatograph mass spectrometer (GC/MS), which is essential to current and future research programs in human and animal nutrition and metabolism at the Indiana University School of Medicine. The instrument requested is a critical component of the Mass Spectrometry Core Laboratory, which has supported NIH funded investigators conducting stable isotopic tracer studies since 1989. The current 13-year-old instrument has not been manufactured in many years, and now the company has discontinued all service support on this instrument. Replacement for this GC/MS is critical to 3 currently funded R01 projects and 1 K23 grant, and to the Mass Spectrometry Core Laboratory's ability to provide analyses for additional and future research. In particular, the Core Laboratory has supported and continues to support the clinical research training of new investigators using stable isotope techniques. Fostering the development of new clinical researchers is an important goal of the NIH and the Indiana University School of Medicine, and new instrumentation will allow this to continue. Finally, a new and more efficient instrument will facilitate the ability of other investigators across the campus to use the laboratory.