Cesium 137 Irradiator: Model 68

描述（由申请人提供）：研究人员要求购买小型动物辐射器，Mark I铯辐射器型号68，以支持NIH资助的干细胞生物学，干细胞移植和癌症研究。这个请求是及时的，因为将要使用这个散热器的七名研究人员最近搬进了CWRU病例医学院的Wolstein研究大楼。这座建筑没有内部通道与凯斯医学院的主要动物设施或两个容纳当前辐射设备的地点相连。由于小鼠和大鼠的辐射是NIH资助的请求研究者的研究的基本要素，这台设备将大大提高及时进行动物研究的能力。该辐照装置将被安置在沃尔斯坦研究大楼的地下一层，内有28000个笼子的清洁屏障设施。散热器将作为凯斯综合癌症中心辐射资源的一部分进行管理。所有住在沃尔斯坦大楼的研究人员将使用该设施进行动物研究。通过在设施内放置辐照器，可以使动物在不暴露于环境中的病原体的情况下维持较长时间。目前，凯斯医学院内没有可供这些研究人员使用的类似设备。出于这个原因，这是一个高度优先的问题，它要求一个基本的设备来支持NIH资助的研究人员的研究。

DESCRIPTION (provided by applicant): The investigators request for the purchase of a small animal radiator, Mark I Cesium Irradiator model 68, to support NIH funded research in stem cell biology, stem cell transplantation and cancer. This request is timely because the seven investigators who will use this radiator have recently moved into the Wolstein Research Building of Case School of Medicine, CWRU. This building is not linked by internal passageways to the major animal facility of the Case School of Medicine or two sites housing current radiation equipment. Since radiation of mice and rats is an essential element to the NIH funded research of the requesting investigators, this piece of equipment will greatly enhance the ability to conduct animal research in a timely fashion. The irradiator will be housed within the twenty-eight thousand-cage clean barrier facility located in the sub-basement of the Wolstein Research Building. The radiator will be managed, as part of the Case Comprehensive Cancer Center Radiation Resource. All investigators housed in the Wolstein Building will utilize this facility for animal research. By placing the irradiator within the facility, it will be possible to maintain animals for prolonged periods of time without exposing these animals to pathogens in the environment. Currently no comparable piece of equipment is located within the Case School of Medicine that is accessible to these investigators. For this reason this is a high priority and its request for an essential piece of equipment to support the research of NIH funded investigators.