ADVANCED FUNCTIONAL MRI EQUIPMENT FOR 3 TESLA SYSTEM: ADHD

这个子项目是利用由NIH/NCRR资助的共享仪器赠款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是用于拨款的，而不一定是用于调查人员的机构。描述(由申请人提供)：来自巴尔的摩马里兰大学校园内的研究人员申请资助购买高级功能磁共振硬件和软件，以增强3.0特斯拉研究专用磁铁。这种新获得的研究磁铁的能力仅限于其主要项目，即作为多中心骨关节炎倡议的一部分扫描膝盖。虽然扫描仪本身是最先进的设备，但它的相关工具非常有限，不会促进这个校园里磁共振研究的增长。此外，即使在完成了产生膝关节结构图像的主要目标之后，扫描仪的大部分时间也是空闲的。这种扫描仪缺乏合适的硬件和软件，严重限制了这种高场磁铁用于研究。NIH赞助的研究人员目前正在使用磁共振成像，他们来自校园内的不同部门，包括放射学、神经学、精神病学、药理学、心脏病学、解剖学和生理学。这些研究人员在有限的时间内使用马里兰大学医疗系统运营的临床1.5特斯拉扫描仪进行研究。由于不断增长的临床需求，在过去几年中，医院扫描仪用于研究的时间变得越来越困难。这种受限的情况导致一些调查人员将他们的研究转移到邻近的机构。医院扫描仪上没有时间给新的调查人员。新的研究专用3.0特斯拉机器承诺通过加强现有研究人员的研究，并增加新研究人员获得急需的磁共振仪器，来改变生物医学磁共振的这种情况。对该仪器的拟议升级有望通过使用功能磁共振成像、扩散张量成像和光谱学等技术来推进人脑功能领域的研究。将这种研究与优化线圈的并行成像相结合的能力，将使巴尔的摩马里兰大学的磁共振研究社区走在功能神经成像研究的前沿。

This subproject is one of many research subprojects utilizing the resources provided by a Shared Instrumentation Grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the grant, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): Researchers from across the campus of University of Maryland, Baltimore request funding for the purchase of Advanced Functional MRI hardware and software to enhance a 3.0 Tesla research-dedicated magnet. This newly-acquired research magnet has capabilities limited to its primary project, which is to scan knees as part of a multi-center Osteoarthritis initiative. While the scanner itself is state of the art equipment, its associated tools are very limited, and will not foster the growth of magnetic resonance research on this campus. Additionally, the scanner is idle for the most part even after fulfilling its primary objective of producing structural images of the knee joints. The lack of suitable hardware and software on this scanner has severely limited the use of this high field magnet for research. NIH sponsored investigators who are currently using magnetic resonance imaging come from various departments within the campus including radiology, neurology, psychiatry, pharmacology, cardiology, anatomy and physiology. These researchers use the clinical 1.5 Tesla scanners operated by the University of Maryland Medical System during limited hours to conduct their research. Availability of hospital scanner time for research has become increasingly difficult over the past few years due to growing clinical demand. This restrictive situation has led some of the investigators to move their research to neighboring institutions. No time is available on the hospital scanner for new investigators. The new research-dedicated 3.0 Tesla machine promises to change this situation for biomedical magnetic resonance by enhancing the research of current investigators, and increasing access to much needed MR instrumentation for new investigators. The proposed upgrade to the instrument promises to advance research in the area of human brain function through use of techniques such as fMRI, diffusion tensor imaging, and spectroscopy. The capability of performing such research in conjunction with parallel imaging with optimized coils will allow the magnetic resonance research community at the University of Maryland, Baltimore to be at the forefront of functional neuroimaging research.