Postdoctoral Training in Cancer Genetics

描述（由申请人提供）：这是俄亥俄州立大学综合癌症中心（OSUCCC）癌症遗传学博士后培训计划的新申请。OSUCCC的30名科学家将联合起来培训下一代癌症遗传学家，重点是研究和治疗乳腺癌、胃肠道和造血癌症的多学科方法。每年将采用独特的招聘工具吸引三名有才华的博士后候选人。认识到对癌症发生和发展的基本机制的完整理解将需要有效地将知识转化为患者的治疗，培训计划已经编制了一个平衡的研究小组，他们在遗传学，细胞信号，细胞生物学和肿瘤模型方面具有专业知识，并且对转化研究有着浓厚的兴趣和良好的记录。将基础知识与转化和/或临床研究相结合的承诺将通过为博士后受训者提供两位具有不同专业知识的共同导师来实现。主要导师和共同导师将共同为受训者提供基础和转化研究方面的优势，弥合这两个领域之间的差距。选定的培训教师在三个癌症主题中都有广泛的正在进行的合作研究。培训计划将加强这些已有的相互作用，促进癌症遗传学研究基础和转化概念的知识和实践交流。学员将参加两周一次的癌症遗传学杂志俱乐部，该俱乐部将由学员独家介绍，还将参加几个短期课程和系列研讨会，包括每月一次的癌症遗传学系列讲座。学员将通过该项目接受必要的技能培训，以建立独立的转化癌症研究项目。

DESCRIPTION (provided by applicant): This is a new application for a postdoctoral training program in cancer genetics at the Ohio State University Comprehensive Cancer Center (OSUCCC). Thirty scientists at the OSUCCC will join forces to train the next generation of cancer geneticists, with an emphasis on multidisciplinary approaches to the study and treatment of breast, gastro-intestinal and hematopoietic cancers. Unique recruiting tools will be employed to attract three talented postdoctoral candidates each year of the program. Recognizing that a complete understanding of the basic mechanisms of cancer initiation and progression will be required for the efficient translation of knowledge to the treatment of patients, the training program has compiled a balanced group of investigators with expertise in genetics, cell signaling, cell biology and tumor models, and with an intense interest and a proven record in translational research. The commitment to coupling basic knowledge to translational and/or clinical research will be realized by providing postdoctoral trainees with two co-mentors having divergent expertise. Together, the primary mentor and co-mentor will provide trainees with strengths in basic and translational research, bridging the gap between these two areas. The selected training faculty has extensive ongoing collaborative studies in each of the three cancer themes. The training program will enhance these pre-existing interactions and foster intellectual and practical exchange of basic and translational concepts to cancer genetics research. The trainees will participate in a bi-weekly Cancer Genetics Journal Club that is to be presented exclusively by trainees, and will also participate in several short courses and seminar series, including a monthly distinguished lecture series on Cancer Genetics. Trainees will be trained by the program with the necessary skills to establish independent research programs in translational cancer research.