Graduate and Postdoctoral Training in Toxicology

描述（由申请人提供）： 这个基础广泛的多学科毒理学培训计划的主要目的是为医学，公共卫生和药学学校的生物医学研究职业做好准备，并在政府或工业实验室中具有良好的环境健康和毒理学原理知识。由13个培训教师代表的研究重点领域包括神经毒性和神经退行性疾病，细胞死亡机制，氧化DNA损伤和修复，以及环境评估和流行病学。 培训教师的13名成员目前由超过700万美元的联邦赠款资助，其中三分之一以上来自NIEHS。 来自疾病控制中心，包括有毒物质和疾病登记署的几位科学家也通过客座讲座和合作研究参与学生培训。 培训的最重要组成部分是实验室研究，首先作为一系列的三个研究轮换，然后在论文实验室。 该培训由毒理学，生物化学，药理学，细胞生物学，分子生物学和生物统计学的核心课程以及毒理学专业领域的高级课程，研讨会课程和期刊俱乐部补充。 该计划旨在支持四名学生和两名博士后研究员，每年从约16名学生和24名博士后研究员的总合格人口。完成博士前培训计划的学生将获得广泛的毒理学和环境卫生知识，深入研究论文领域的知识，搜索，批判性阅读和生物医学科学文献报告的能力，掌握各种在现代生物医学研究中有用的实验室技术，规划和执行研究项目的技能，能够写清楚，发表准确的科学报告，并有能力有效地提出研究结果。完成培训计划的博士后研究员将在尖端毒理学研究方面获得丰富的经验，并应提交个人NRSA申请，以获得资助写作经验，以帮助过渡到独立的研究职位。

DESCRIPTION (provided by applicant): The primary purpose of this broadly based multidisciplinary toxicology training program is to prepare trainees for biomedical research careers in schools of medicine, public health, and pharmacy, and in governmental or industrial laboratories with a sound knowledge in environmental health and principles of toxicology. The areas of research emphasis represented by the 13 training faculty include neurotoxicity and neurodegenerative disease, mechanisms of cell death, oxidative DNA damage and repair, and environmental assessment and epidemiology. The 13 members of the training faculty are currently funded by over $7,000,000 in federal grants with more than a third of that being from NIEHS. Several scientists from the Centers for Disease Control, including the Agency for Toxic Substances and Diseases Registry, also participate in the training of students through guest lectures and collaborative research. The most important component of training is laboratory research, first as a series of three research rotations, then in the dissertation laboratory. This training is complemented by core courses in toxicology, biochemistry, pharmacology, cell biology, molecular biology, and biostatistics, and advanced courses in toxicology specialty areas, seminar courses, and journal clubs. The program is designed to support four students and two postdoctoral fellows each year from a total eligible population of about 16 students and 24 postdoctoral fellows. The student who completes the predoctoral training program will have acquired broad familiarity with toxicology and environmental health, knowledge in depth in the area of dissertation research, the ability to search, read critically and report on the literature of the biomedical sciences, mastery of a variety of laboratory techniques useful in modern biomedical research, skill in planning and executing a research project, ability to write clear, accurate scientific reports for publication, and ability to present effectively the results of research. The postdoctoral fellow who completes the training program will have gained extensive experience in cutting edge toxicology research, and should have submitted an individual NRSA application to gain grant writing experience to aid in the transition into an independent research position.