SUBMICRON SENSOR POSITIONING WITH REPEATABILITY AND STABILITY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。计算机控制的亚微米定位将使我们能够研究用作位置调节器的非接触式细胞膜检测方法。为此，我们打算探索使用压电管定位器，除了我们的直线步进电机的方法。为了在3个轴上驱动压电管，需要5个两极电压源。PIC16f73的脉宽调制器用于构建一对能够产生高达500伏的升压转换器。PIC通过片上模数转换器监控电压，并在其脉冲宽度监视器上调整占空比，以达到主机要求的电压。对于超精细控制，可以使用模拟输入通过一对晶体管来设置电压。在此模式下，PIC会将升压转换器的电压设置为高于请求值2伏，以减少发热。添加了精细的位置属性，使定位器能够与现有的BRC微操作器顺利工作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Computer controlled submicron positioning will enable us to investigate methods of non-contact cell membrane detection for use as a position regulator. To this end we intend to explore the use of piezo tube positioners in addition to our linear stepper motor approach. To drive a piezo tube in 3 axes, 5 bipolar voltage sources are needed. The pulse width modulators from a PIC16f73 are used to construct a pair of boost converters capable of producing up to ¿500 Volts. The PIC monitors the voltage through an on-chip analog to digital converter and adjusts the duty cycle on its pulse width monitor to achieve the voltage requested by the host computer. For ultra fine control, analog inputs may be used to set the voltage through a pair of transistors. In this mode the PIC will set the boost converters potential 2 volts above the requested value to reduce heating. A fine position property has been added to allow the positioner to work smoothly with the existing BRC micro-manipulator.