THE SAFETY AND EFFICACY OF THE LOW AND HIGH CARBOHYDRATE DIETS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。低碳水化合物和高碳水化合物饮食减肥的安全性和有效性是一项研究，旨在评估最流行的高蛋白、低碳水化合物饮食（阿特金斯饮食）与更标准的高碳水化合物、低脂肪饮食行为方法相比的有效性。尽管阿特金斯饮食法非常受欢迎，但在科学文献中很少有评价。几乎所有的数据都来自解毒剂报告。科罗拉多大学健康科学中心的人类营养中心是参与这项为期5年的研究的三个地点之一。每个研究中心将在2年内跟踪120名参与者（60名男性和60名女性）。一半的参与者将被随机分配到阿特金斯饮食组，另一半则根据美国农业部提出的饮食指南进行饮食。所有参与者将在不同时间点评估体重和身体成分、代谢和器官功能以及运动能力的变化。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Safety and Efficacy of Low and High Carbohydrate Diets for weight loss is a research study that was designed to evaluate the effectiveness of the most popular high protein, low carbohydrate diet, the Atkins' Diet, as compared to a more standard behavioral approach of a high carbohydrate, low fat diet. Despite the extreme popularity of the Atkins' Diet there has been very little evaluation in the scientific literature. Almost all data comes from antidotal reports. The Center for Human Nutrition at the University of Colorado Health Sciences Center is one of three sites participating in this 5-year research study. Each site will be following 120 participants (60 men and 60 women) over a 2-year time period. Half of the participants will be randomized to the Atkins' diet and the other half to a diet based on dietary guidelines put forth by the USDA. All participants will be evaluated for changes in weight and body composition, metabolic and organ function, and ability to exercise at various time poin