Healthy heart, healthy brain - using genetic data to investigate the causal relationship between cardiovascular and neurodegenerative disease

越来越多的证据支持心血管疾病(CVD)与神经退行性疾病之间的密切联系。然而，来自观察性研究的证据并不一致。该项目将使用基因数据来研究这种联系。项目成果可能会指出研究和预防的新途径，借此改变生活方式、减少心血管疾病的药物干预也可能为减轻神经退行性疾病的负担带来希望。

There is growing evidence supporting a strong association between cardiovascular disease (CVD) with neurodegenerative disease. However, evidence from observational studies has been inconsistent. This project will use genetic data to investigate this link. The project outcomes may point to new avenues for research and prevention, whereby lifestyle modifications pharmaceutical interventions which decrease CVD might also hold promise for reducing the burden of neurodegenerative disease.