Michigan Interdisciplinary Center on Social Inequality, Mind & Body

我们建议继续和扩大目前资助的一系列成功的跨学科合作，作为P-50密歇根跨学科中心的社会不平等，心灵和身体。与从P50中心到R24中心的转变相一致，MICSIMB将强调资助研究项目的支持核心，这些项目的研究改进以及探索性/试点研究。R-24 MICSIMB将支持一个创新的跨学科研究计划的扩展，该计划旨在了解与健康有关的社会心理因素（信仰、态度、情感状态、价值观、压力和社会关系）、其更广泛的社会、社区和心理前因以及与健康相关的社会心理因素之间的关系。 心理社会因素及其前因导致身体和精神障碍发展的病理生理途径。该研究将涵盖从婴儿期和儿童期到成年期和老年期的整个生命过程中的人类发展，考虑广泛的身心健康结果，重点关注衰老，人类发展和心血管疾病，并重点关注健康差异，生命过程方法，空间分析/邻里效应，基因环境相互作用和方法创新。研究增强将利用密歇根大学现有的大量正在进行的活动和存档数据，这些数据代表了超过20万人的各种代表性研究人群的信息。这些活动涵盖了一系列主题，从分析邻里和社区因素以及心理社会因素在健康中的作用，到基因与社会经济因素之间的相互作用。 高血压和痴呆的心理社会环境。这种方法将建立在以前大量研究的基础上，代表了一种非常具有成本效益的方法，可以解决我们一直成功进行的身心研究扩展计划中的关键问题。参与将是一个非常有成就的跨学科小组的22个核心研究人员，跨越16个单位在整个大学谁已经发表了1,000多篇科学论文，已被引用超过22,000次，至少85%的这些论文相关的拟议中心扩建。

We propose to continue and expand a successful series of interdisciplinary collaborations currently funded as the P-50 Michigan Interdisciplinary Center on Social Inequalities, Mind, and Body. Consistent with the change from a P50 to an R24 Center, the MICSIMB will emphasize support cores for funded research projects, research enhancements to these projects, and exploratory/pilot studies. The R-24 MICSIMB will support the expansion of an innovative interdisciplinary research program seeking to understand the relationships of psychosocial factors related to health (beliefs, attitudes, affective states, values, stress and social relationships), their broader social, community, and psychological antecedents, and the pathophysiologic pathways through which psychosocial factors and their antecedents contribute to the development of physical and mental disorders. The research will encompass human development over the full life course from infancy and childhood through adulthood and older age, consider a broad range of physical and mental health outcomes, with some emphasis on aging, human development, and cardiovascular disease, and have important foci on health disparities, life course approaches, spatial analysis/neighborhood effects, gene-environment interaction, and methodological innovation. The research enhancements will make use of a large set of ongoing activities and archived data available at the University of Michigan, representing information on diverse, representative study populations of over 200,000 people. The activities cover a range of topics from analysis of the role of neighborhood and community factors and psychosocial factors in health, to interactions between genes and the socioeconomic and psychosocial environment in hypertension and dementia. Such an approach will build on the previous efforts of a large number of studies and represents a very cost-effective approach to addressing critical issues in the expanded program of mind-body research that we have been carrying on so successfully. Participating will be a very accomplished interdisciplinary group of 22 core investigators, spanning 16 units across the University who have published over 1,000 scientific papers that have been cited more than 22,000 times with at least 85% of these papers relevant to the proposed Center expansion.