SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER

描述（由申请人提供）：授予P51 RR 00163 -50的5年续期 要求为ONPRC支持生物医学研究的项目提供资金。该应用程序反映了 一个新的战略重点是跨学科研究，以优化非人类的使用和发展， 灵长类动物（NHP）模型。该应用程序的目的是：1）提供基础设施支持 进行先进的生物医学研究是必要的，其中NHP用于加速进展 （2）加强对疾病的认识;（3）加强对疾病的认识。的资源（科学专门知识，实验室， 动物服务，研究支持核心和设备），以作为区域和国家 资源; 3）通过我们的支持， 扩大SPF印度恒河猴繁殖计划的计划;以及4）扩大研究 在干细胞生物学、衰老、肥胖、遗传学、传染病、疫苗中利用NHP的项目 发展、神经科学和妇女？的健康。为了实现这些目标，需要在以下方面提供支助： 三大领域。首先，管理和中心运营提供管理和服务 为ONPRC的各个方面提供所需的支持。单位包括：1）主任？2）行政管理 服务（商业服务、环境健康和辐射安全、设施和财产， 信息技术与工程，以及研究图书馆）; 3）动物资源 （行政、运营、行为服务、病理学服务、外科服务和临床 4）研究支持核心（辅助生殖技术，内分泌技术， 成像和形态学，免疫学，磁共振成像，分子和细胞生物学，以及 病毒学和血清学）。其次，科学部分包括支持：1）科学部门 （神经科学，病理生物学和免疫学，生殖科学）及其跨学科 工作组（衰老生物学，代谢疾病，干细胞和发育生物学）; 2） 合作研究单位，促进外部资助的研究; 3）试点项目计划; （4）资源相关研究。最后，改进和现代化包括以下资金 设备以及改建和翻修。

DESCRIPTION (provided by applicant): The 5-year renewal for Grant P51 RR00163-50 requests funding for programs at the ONPRC that support biomedical research. The application reflects a new strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) provide the infrastructure support necessary to conduct advanced biomedical research for which NHPs are used to accelerate progress in understanding human diseases; 2) enhance the Center?s resources (scientific expertise, laboratories, animal services, research support cores and equipment) so as to serve as a regional and national resource; 3) increase the availability of defined NHPs for biomedical research through support of our programs to expand the SPF Indian-origin rhesus macaque breeding program; and 4) expand research programs utilizing NHPs in stem cell biology, aging, obesity, genetics, infectious diseases, vaccine development, neuroscience and women?s health. To accomplish these aims, support is requested in three broad areas. First, Administration & Center Operations provide the administrative and service support required for all aspects of the ONPRC. Units include: 1) the Director?s Office; 2) Administrative Services (Business Services, Environmental Health & Radiation Safety, Facilities & Property, Information Technology & Engineering, and the Research Library); 3) Animal Resources (Administration, Operations, Behavioral Services, Pathology Services, Surgery Services, and Clinical Medicine); and 4) Research Support Cores (Assisted Reproductive Technology, Endocrine Technology, Imaging & Morphology, Immunology, Magnetic Resonance Imaging, Molecular & Cellular Biology, and Virology & Serology). Secondy, Scientific Components include support for: 1) Scientific Divisions (Neuroscience, Pathobiology & Immunology, and Reproductive Sciences) and their interdisciplinary Working Groups (Biology of Aging, Metabolic Disease, and Stem Cell & Developmental Biology); 2) the Collaborative Research Unit that facilitates externally funded research; 3) the Pilot Project Program; and 4) Resource-Related Research. Finally, Improvement & Modernization includes funds for equipment and alterations and renovations.