HIV/AIDS Prevention Program Archive for Developing Countries (HAPPA-DEV)

描述（由申请人提供）：研究表明，艾滋病毒/艾滋病行为预防计划可以对减少成年人和青年人的艾滋病毒风险行为产生重大影响（CDC，2008 a; Kelly & Kalichman，2002; Kirby，2001;莱尔斯et al.，2007年）。艾滋病毒预防技术转让的最新进展，这是一个由研究人员确定有效干预措施、为从业人员受众翻译、传播和重新实施的过程（Card等人，2001; Neumann & Sogolow，2000），开始弥合美国（US）研究与实践之间的差距（Institute of Medicine，2001）。发展中国家的保健从业人员、教育工作者和研究人员没有类似的资源。拟议的项目将为发展中国家的卫生从业人员和研究人员提供关键资源，以促进获得、复制和重新评估有效的艾滋病毒预防行为干预措施。具体而言，该项目将（1）为发展中国家建立艾滋病毒/艾滋病预防方案档案（HAPPA-DEV），一套艾滋病毒预防计划工具包，其中包含复制和重新评估已被证明有效的行为干预计划所需的所有材料（通过严格的评估研究）预防艾滋病毒感染或其风险-发展中国家青年和成年人的相关行为前因;（2）开发创新的，基于研究的程序适应工具包>在一个定制的版本，以增加HAPPA-DEV程序框，以及在一个独立的版本，以经验使用-从其他来源获得的经过验证的方案>将建立从业者的能力，使其能够针对新的目标人群和背景制定有效的行为方案，同时保持对方案核心组成部分的忠诚;以及（3）开发一个程序定位器和使用工具，以帮助用户在档案中确定最适合其需要和环境的预防干预措施，并为用户提供每个HAPPA-DEV程序的使用和实施提示。在第一阶段，科学家专家小组确定并选择了有效的干预措施，开发了所有产品的原型，并与艾滋病毒预防专业人员进行了可用性测试。在第二阶段，科学家专家小组将确定和选择第二套程序，纳入HAPPA-DEV汇编;将根据第一阶段可用性测试的结果修改第一阶段开发的产品原型;将对修改后的产品进行可用性测试;所有产品将全部定稿和开发;并将进行一项传播/实施研究，以评估实施HAPPA-DEV方案的机构的方案适应过程和经验。 公共卫生相关性：发展中国家的艾滋病预防工作者在确定在他们或其他地区已被证明有效的行为干预措施，从有效的干预计划中获取材料以及使干预措施适应目标人群和环境方面几乎没有帮助。在该项目的支持下开发的资源将为发展中国家的卫生从业人员和研究人员（及其美国合作者）提供关键资源，以促进有效的艾滋病预防行为干预措施的获得、复制和重新评估。

DESCRIPTION (provided by applicant): Research has shown that HIV/AIDS behavioral prevention programs can have a significant impact on reducing HIV risk behaviors among adults and youth (CDC, 2008a; Kelly & Kalichman, 2002; Kirby, 2001; Lyles et al., 2007). Recent advances in HIV prevention technology transfer, a process by which effective interventions are identified by researchers, translated for practitioner audiences, disseminated, and re-implemented (Card et al., 2001; Neumann & Sogolow, 2000), are beginning to bridge the gap between research and practice in the United States (US) (Institute of Medicine, 2001). No similar resources exist for health practitioners, educators, and researchers in developing countries. The proposed project will provide health practitioners and researchers from developing countries with key resources that facilitate access to, replication of, and re-evaluation of efficacious behavioral HIV prevention interventions. Specifically, the project will (1) Develop the HIV/AIDS Prevention Program Archive for Developing Countries (HAPPA-DEV), a collection of HIV prevention program kits containing all the materials needed to replicate and re-evaluate behavioral intervention programs that have been shown to be efficacious (by rigorous evaluation research) in preventing HIV infection or its risk-related behavioral antecedents among youth and adults in developing country settings; (2) Develop an innovative, research-based Program Adaptation Toolkit>in a customized version to augment HAPPA-DEV program boxes as well as in a stand- alone version to use with empirically-validated programs acquired from other sources>that will build practitioners' capacity to tailor effective behavioral programs to new target populations and contexts, while retaining fidelity to the programs' core components; and (3) Develop a program LOCator and USage (LOCUS) tool to assist users in identifying prevention interventions in the archive best suited to their needs and settings, and to give users usage and implementation tips for each HAPPA-DEV program. In Phase I, efficacious interventions were identified and selected by a Scientist Expert Panel and prototypes of all products were developed and subjected to usability testing with HIV prevention professionals. In Phase II, the Scientist Expert Panel will identify and select a second set of programs for inclusion in the HAPPA-DEV collection; the product prototypes developed in Phase I will be modified per the results of the Phase I usability tests; usability tests will be conducted on the revised products; all products will be finalized and developed in their entirety; and a dissemination/implementation study will be conducted to assess the program adaptation process and experiences of agencies implementing the HAPPA-DEV programs. PUBLIC HEALTH RELEVANCE: HIV prevention practitioners in the developing world have had little help in identifying behavioral interventions that have been shown to be effective in their or other regions, in acquiring materials from effective intervention programs, and in adapting the interventions to their target populations and contexts. The resources developed under the auspices of this project will provide health practitioners and researchers from developing countries (and their US collaborators) with key resources that facilitate access to, replication of, and re-evaluation of efficacious behavioral HIV prevention interventions.