Quantitative Biology: a Graduate Curriculum Linking the Physical and Biomedical S

描述（由申请人提供）：上个世纪的后半叶产生了大量关于生命的细胞和分子过程的信息。这些数据的数量和质量正在生物医学科学中引入一种新的思维模式，这种模式严重依赖数学和计算工具以及严格的定量实验方法。分析工具和实验方法越来越多地不是在生命科学中土生土长的，而是从物理科学的研究中采用的。这个勇敢的新世界需要一种新的研究人员，他们可以轻松地在工作台和工作站之间移动，他们可以像运行模拟一样轻松地运行显微镜，他们可以通过设计同样定量的实验来建立定量模型并进行测试。布兰迪斯大学的定量生物学（QB）项目汇集了六个不同的博士学位。四个科学系的课程，以培养学生谁可以上升到这个跨学科的挑战。QB是布兰迪斯的一个官方跨部门研究生课程，刚刚完成了第二个完整学年的运作;该计划目前有21名注册学生。QB利用 现有学科博士的优势布兰迪斯的课程，将这些学生聚集在一起， 专业课程中的课程，旨在利用多学科团体培训提供的学习机会。生物化学、生物物理与结构生物学、化学、分子与细胞生物学、神经科学或物理学博士研究生课程。计划和谁选择QB轨道将，成功完成后，获得博士学位。在他们选择的学科学位“与定量生物学的额外专业化”。这种方法为学生提供了现代学科衔接培训，同时为毕业生提供博士学位。在就业市场上证明有价值的证书，因为它是公认的传统学科。学生通常在博士学位的第一年或第二年进入QB课程。学习，并保持与QB附属，直到他们毕业。每一个被选中接受培训补助金支助的学生将在其学习的第二年和第三年得到支助。 相关性：定量生物学计划的目标是培养博士。科学家们装备精良，将物理和化学中的定量实验，计算和数学方法应用于生物医学研究中的重要问题。预计这些科学家的工作将导致公共卫生的改善，通过推进基础研究的方向是不容易获得的科学家谁缺乏跨学科的培训。

DESCRIPTION (provided by applicant): The second half of the last century produced a staggering wealth of information about the cellular and molecular processes of life. The quantity and quality of this data is ushering in a new mode of thinking in the biomedical sciences that relies heavily on mathematical and computational tools and on rigorous quantitative experimental methods. With increasing frequency, the analytical tools and experimental methods are not home grown within the life sciences, but are adopted from research in the physical sciences. This brave new world requires a new kind of researcher, one who easily moves between the bench and the workstation, one who is equally at ease with running microscopes as with running simulations, and one for whom building quantitative models and testing them by designing equally quantitative experiments comes naturally. The Quantitative Biology (QB) Program at Brandeis University brings together six different Ph.D. programs from four science departments in order to train students who can rise to this interdisciplinary challenge. QB is an official interdepartmental graduate program at Brandeis that has just completed its second full academic year of operation; the program currently has 21 enrolled students. QB leverages the strengths of existing disciplinary Ph.D. programs at Brandeis by bringing together students from these programs in a specialized curriculum that is designed to take advantage of the learning opportunities afforded by training in multi-disciplinary groups. Students admitted to graduate study in the Biochemistry, Biophysics & Structural Biology, Chemistry, Molecular & Cellular Biology, Neuroscience, or Physics Ph.D. programs and who choose the QB track will, upon successful completion, receive a Ph.D. degree in their chosen discipline "with an additional specialization in Quantitative Biology". This approach provides the students with modern discipline-bridging training while providing the graduate with a Ph.D. credential that has proven value on the job market because it is in a recognized traditional discipline. Students typically enter the QB program in either the first or second years of their Ph.D. studies and remain affiliated with QB until they graduate. Each student selected for support by the training grant will be supported during years 2 and 3 of their studies. RELEVANCE: The goal of the Quantitative Biology program is to train Ph.D. scientists who are well equipped to bring quantitative experimental, computational, and mathematical methods from Physics and Chemistry to bear on important problems in biomedical research. It is anticipated that the work of these scientists will lead to improvements in public health by advancing basic research in directions that are not readily accessible to scientists who lack interdisciplinary training.