Mechanisms of Aging and Demetina Training Program

描述（由申请人提供）：本申请是西北大学神经科学研究所（NUIN）的博士后和博士前老龄化和痴呆症培训计划的持续资助请求。申请资助四名已开始全职论文研究的高级博士预科候选人和四名处于早期或后期培训阶段的博士后实习生。该培训计划由多学科研究人员组成，他们的工作重点是衰老和痴呆的机制，包括阿尔茨海默病，帕金森病和肌萎缩侧索硬化症，方法跨越分子，细胞，系统，行为，神经心理学和临床神经科学，包括四名获得当前NIH MERIT奖的研究人员和一名霍华德休斯研究员。24位教师导师中有7位是女性，包括副主任。这些教员隶属于NUIN，认知神经学和阿尔茨海默病中心，该中心有NIA支持的阿尔茨海默病中心拨款，Buehler衰老研究中心和Udall帕金森病中心。该项目将由John Disterhoft博士指导，Sandra Weintraub博士（副主任）、内部指导委员会和外部咨询委员会协助。4名博士后和4名博士生将在西北大学芝加哥校区和埃文斯顿校区2个学院10个系的24名导师的指导下进行研究。博士后研修生将根据之前的培训和研究计划进行选拔。博士预科生将根据课程表现、轮转和拟进行的论文研究的相关性，从NUIN和医学家博士培养计划中选择。对于研究计划是跨学科的，并在一个以上导师实验室进行的学员，将给予特别考虑。将作出协调一致的努力来征聘妇女和少数民族。该项目将提供一系列跨学科的研究和培训机会，包括衰老和痴呆研究的基础和临床方法。指导教师将通过正式的建议和评估，通过课堂和非正式的讨论来协助和监督学员的进步。除了提供研究培训外，该项目还将帮助受训者发展书面和口头沟通、拨款写作、网络和职业发展方面的技能。培养对神经科学家面临的伦理问题和负责任的科学行为的清晰认识将是另一个培训目标。

DESCRIPTION (provided by applicant): This application is a request for continued funding of a broadly based postdoctoral and predoctoral Mechanisms of Aging and Dementia Training Program from the Northwestern University Institute for Neuroscience (NUIN). Funding to support four advanced predoctoral candidates, after they have begun full time thesis research, and four postdoctoral trainees, in early or later stages of training, is requested. This training program has developed from a multidisciplinary group of investigators whose work focuses on the mechanisms of aging and dementia, including Alzheimer's Disease, Parkinson's Disease and Amyotrophic Lateral Sclerosis, with approaches spanning molecular, cellular, systems, behavioral, neuropsychological and clinical neuroscience, including four with current NIH MERIT awards, and one Howard Hughes Investigator. Seven of 24 faculty preceptors are women, including the Associate Director. These faculty are affiliated with NUIN, the Cognitive Neurology and Alzheimer's Disease Center, that has an NIA supported Alzheimer's Disease Center grant, the Buehler Center on Aging and the Udall Parkinson's Disease Center. The program will be directed by John Disterhoft, PhD with the assistance of Sandra Weintraub, PhD (Associate Director), an internal Steering Committee and an External Advisory Committee. The four postdoctoral and four predoctoral trainees will conduct their research under the guidance of 24 preceptors from 10 departments of 2 schools on the Chicago and Evanston campuses of Northwestern University. Postdoctoral trainees will be selected on the basis of previous training and a research plan. Predoctoral trainees will be selected from NUIN and the Medical Scientist PhD Training Program on the basis of course performance, rotation and the relevance of proposed dissertation research. Special consideration will be given to trainees whose research plans are interdisciplinary and carried out in more than one preceptor laboratory. A concerted effort will be made to recruit women and minorities. The program will offer a board range of interdisciplinary research and training opportunities in both the fundamental and clinical approaches to aging and dementia research. The preceptor faculty will assist and monitor trainee progress through formal advising and evaluations, through the classroom and through informal discussions. In addition to providing research training, the program will help trainees develop skills in written and oral communication, grant writing, networking, and career development. Instilling a clear awareness of ethical issues facing neuroscientists and responsible conduct in science will be another training goal.