COHORT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 COHORT是亨廷顿研究小组在全球范围内的研究中心的一项协调研究工作，旨在前瞻性地收集受亨廷顿病（HD）影响且属于HD家族成员的知情同意个体的数据。 年度评估的数据将涉及具有遗传和环境因素的家庭之间的临床特征（表型）。 从这些关系中获得的知识将更好地为我们提供有关HD发病和进展的信息，帮助确定HD的潜在干预措施，并帮助规划旨在减缓HD发病的实验性治疗的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. COHORT is a coordinated research effort by Huntington Study Group research centers worldwide to prospectively collect data from consenting individuals who are affected by Huntington's disease (HD) and who are part of an HD family. The data from annual assessments will relate clinical characteristics (phenotypes) between families with genetic and environmental factors. The knowledge from these relationships will better inform us about the onset and progression of HD, help identify potential interventions for HD, and aid in planning research studies of experimental treatments aimed at slowing the onset of HD.