SINGLE CRYSTAL XAS OF CUSF

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 初步的晶体学测量表明，一个前所未有的金属结合位点的铜外排蛋白CusF，一种新的有机金属结构。然而，该晶体具有适度的分辨率，更重要的是在金属附近是无序的，只有部分金属位置占据。溶液和单晶XAS的组合将被用来提供详细的局部结构信息，显然是前所未有的金属网站。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Initial crystallographic measurements suggest an unprecedented metal binding site in the Cu efflux protein CusF, with a novel organometallic structure. However, the crystal has modest resolution and more importantly is disordered near the metal, with only partial metal-site occupancy. A combination of solution and single crystal XAS will be used to provide detailed local structural information for the apparently unprecedented metal site.