课题基金 / 基金详情

SENSITIVITY AMPLIFICATION IN SIGNAL TRANSDUCTION CASCADES

SENSITIVITY AMPLIFICATION IN SIGNAL TRANSDUCTION CASCADES
信号传导级联中的灵敏度放大
批准号：
7956415
负责人：
BORIS SLEPCHENKO
金额：
$1.63万
依托单位：
UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-05-01 至 2010-04-30
来源：
https://reporter.nih.gov/project-details/7956415
关键词：
CellsComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantInstitutionModelingPropertyResearchResearch PersonnelResourcesSignal TransductionSourceStudy modelsUnited States National Institutes of Health

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是对信号转导级联中灵敏度放大的模拟研究。虽然灵敏度放大长期以来一直被认为是信号转导级联的一个几乎普遍的特性，但即使对相对简单的网络来说，全面的参数分析仍然是一个挑战。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a modeling study of sensitivity amplification in signal transduction cascades. While sensitivity amplification has long been regarded as a virtually universal property of signal transduction cascades, a comprehensive parameter analysis remains a challenge even for relatively simple networks.
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