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RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS

RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS
基于 FRAP 测量的体内肌动蛋白聚合率
批准号:
8169584
负责人:
BORIS SLEPCHENKO
金额:
$1.63万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-05-01 至 2011-04-30

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项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者(PI)可能从另一个NIH来源获得了主要资金, 因此可以在其他CRISP条目中表示。列出的机构是 中心,不一定是研究者的机构。 该研究涉及确定在稳态条件下,基于FRAP测量的体内肌动蛋白聚合的速率。这种协作研究涉及开发具有在虚拟细胞中推广和实施潜力的细胞生物学模型。 这种研究,其中模型是必要的数据分析和/或更好的定性理解细胞现象,作为激励因素(并在同一时间作为试验台),为进一步发展的虚拟细胞。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The study involves determination of a rate of in vivo actin polymerization in steady-state conditions, based on FRAP measurements. This collaborative study collaborative studies involves development of cell-biological models that have potential for generalization and implementation in the Virtual Cell. Such studies, where models are necessary for data analysis and/or better qualitative understanding of cell phenomena, serve as motivators (and at the same time as testbeds) for further development of the Virtual Cell.
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会议论文
MESH REFINEMENT AND PARALLELIZATION OF VCELL PDE SOLVERS
RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS
BIOPHYSICAL MECHANISMS FOR MODELS OF CYTOSKELETAL DYNAMICS
NUMERICAL TOOLS FOR NEW CELL BIOLOGICAL MODELING CAPABILITIES IN VCELL
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