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RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS

RATE OF IN VIVO ACTIN POLYMERIZATION BASED ON FRAP MEASUREMENTS
基于 FRAP 测量的体内肌动蛋白聚合率
批准号:
8362511
负责人:
BORIS SLEPCHENKO
金额:
$1.05万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-05-01 至 2012-04-30

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的, 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量, 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 这项研究包括基于FRAP测量,在稳态条件下确定体内肌动蛋白聚合的速度。这种协作研究协作研究包括开发具有在虚拟细胞中推广和实施的潜在的细胞-生物模型。这类研究对于数据分析和/或更好地定性了解细胞现象是必要的,是进一步发展虚拟细胞的动力(同时也是试验床)。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The study involves determination of a rate of in vivo actin polymerization in steady-state conditions, based on FRAP measurements. This collaborative study collaborative studies involves development of cell-biological models that have potential for generalization and implementation in the Virtual Cell. Such studies, where models are necessary for data analysis and/or better qualitative understanding of cell phenomena, serve as motivators (and at the same time as testbeds) for further development of the Virtual Cell.
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会议论文
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