Biology of Infectious Disease and Inflammation

描述(由申请人提供)：本提案请求继续支持新墨西哥大学传染病和炎症(IDIP)方面的扩大培训补助金(TG)。自成立以来的10年里，这一培训计划为博士后和博士后学员提供了从事前沿、跨学科和以技术为中心的传染病(ID)研究的机会，并向各种科学家学习。一个基本的主题是促进使用不同实验方法研究传染病、宿主反应和生物治疗的研究人员之间的互动。跨越部门和机构的界限，TG现在利用了32名资助的调查人员的专业知识。培训人员在四个医学院系任职，包括内科(8个)、细胞生物学和生理学(1个)、病理学(9个)和分子遗传学和微生物学(7个)；药学院(1个)；新墨西哥大学化学和核工程系(1个)；洛夫莱斯呼吸研究所(5个)。教师培训人员分为四个领域：1)ID和免疫方面的翻译研究--将基本的研究成果带入临床研究，然后付诸实践；2)感染的细胞生物学--在细胞间水平上研究ID；3)新出现的ID的发病机制--疾病病因的致病机制；4)桥接技术--将尖端技术结合到ID的研究中。博士后和博士后实习生都需要在生物医学研究生项目的常规(博士前)课程之外完成IDIP的特定课程，包括特定的期刊俱乐部和正在进行的课程。尽管我们的TG年轻，但我们在招募代表不足的少数族裔(URM)成员加入该计划方面取得了实质性的成功，我们的毕业生，包括少数群体成员，已经开始出现在肯塔基大学或斯克里普斯研究所等机构的教职员工队伍中。我们相信，我们的TG已经取得了巨大的势头，并准备通过其更多的培训人员和更多的机会接触到高质量的少数族裔和非少数族裔学生，实现更大的影响。对我们项目的支持将产生可观的回报，扩大高度跨学科的年轻调查人员队伍。

DESCRIPTION (provided by applicant): This proposal is a request for continued support of an expanded training grant (TG) in Infectious Disease and Inflammation (IDIP) at the University of New Mexico. In the 10 years since its inception, this training program provided pre- and postdoctoral trainees opportunities to engage in cutting edge, interdisciplinary and technology-centered infectious disease (ID) research and learn from a wide variety of scientists. An underlying theme has been the promotion of interactions between researchers who are using different experimental approaches to study infectious disease, host responses and biothreats. Crossing departmental and institutional lines, the TG now draws upon the expertise of thirty-two funded investigators. The training faculty have appointments in four School of Medicine departments that include Internal Medicine (8), Cell Biology and Physiology (1), Pathology (9) and Molecular Genetics and Microbiology (7); the College of Pharmacy (1); the UNM department of Chemical and Nuclear Engineering (1); and Lovelace Respiratory Research Institute (5). Faculty trainers fall into four areas of interest: 1) Translational Studies in ID and Immunity -bringing basic findings into clinical research, then to practice; 2) Cell Biology of Infection the study of ID at the intercellular level; 3) Pathogenesis of Emerging ID -pathogenic mechanisms of disease causation and 4) Bridging Technologies - the incorporation of cutting edge technologies to the study of ID. Both predoctoral and postdoctoral trainees are expected to complete IDIP-specific courses in addition to their regular (predoctoral) course work in the Biomedical Sciences Graduate Program including specific journal clubs and works in progress sessions. Despite the youth of our TG, we have enjoyed substantial success at recruiting members of under- represented minorities (URM) to the program, and our graduates, including members of minority groups, have already begun to appear among the ranks of the faculty of institutions such as the University of Kentucky or the Scripps Research Institute. We believe our TG has achieved great momentum and is poised to realize even greater impact with its far larger cadre of trainers and greater access to high-quality minority and non-minority students. Support for our program will yield substantial rewards, expanding the ranks of highly interdisciplinary young investigators.