Nanoengineering Core

核心标题：纳米工程核心 核心摘要：多阶段矢量(MSV)，即介孔硅颗粒，对单一类型和多类型组合的纳米颗粒起到‘积分器’和导向功能。在TCCN的所有项目中都有MSV。MSV是使用法拉利集团开发的光刻和电化学方法在德克萨斯大学奥斯汀分校的国家纳米技术核心设施中制造的，在那里，法拉利博士拥有一个由TCCN研究员刘学武助理教授协调的12人团队。MSVS的制造涉及高度专业化的设备和非常复杂的多步骤协议。因此，有必要在Ferrari博士的指导下，与West博士合作，在MSVS中整合第二阶段纳米颗粒，建立TCCN的介孔硅生产业务，作为纳米工程核心。除了微粒系统，纳米工程核心公司还将制造和表征用于蛋白质组学和多肽液晶的介孔二氧化硅纳米芯片，这些芯片被用于TCCN的所有项目，用于监测治疗和预防效果，并识别用于卵巢癌和胰腺癌早期检测的多分子标志物。这些纳米芯片也是由法拉利集团在国家 位于奥斯汀的纳米技术核心设施。

CORE TITLE: Nanoengineering Core CORE SUMMARY: The Multi-Stage Vectors (MSV), mesoporous silicon particles, serve as an 'integrator', and vectoring function for single types and multiple-type combinations of the nanoparticles. The MSVs are present in all TCCN projects. MSVs are manufactured using photolithographic and electrochemical methods developed by the Ferrari group in a National nanotechnology core facility at the University of Texas in Austin, where Dr. Ferrari maintains a team of 12 personnel coordinated by TCCN investigator Assistant Professor Xuewu Liu. The manufacture of MSVs involves highly specialized equipment and very complex multi-step protocols. Therefore, it is necessary to establish the mesoporous silicon-producing operation ofthe TCCN as a Nanoengineering Core, directed by Dr. Ferrari, in collaboration with Dr. West for what pertains to the integration of second-stage nanoparticles in the MSVs, and Dr. Liu. In addition to the particulate systems, the Nanoengineering Core will manufacture and characterize the mesoporous silica nanochips for proteomics and peptidomlcs, which are utilized in all TCCN projects for the monitoring of therapeutic and preventative efficacy, and the identification of multi-molecular signature markers for the early detection of ovarian and pancreatic cancer. These nanochips were also developed by the Ferrari group in the National nanotechnology core facility in Austin.