Predoctoral Training Program in Biotechnology

描述（由申请人提供）：本申请要求继续支持生物技术博士前培训计划，首次资助于1990年。29名参与教师来自六个部门和四个学院：化学，（文理学院）;生物化学，微生物学（医学院）;土木与环境工程，化学与生物化学工程（工程学院）;医药和天然产物化学（药学院）。这个多元化的教师提供的学科背景，导致博士学位的学员。在各自的部门。以下要求的活动提供了适合生物技术导向职业的跨学科背景：a）生物技术三个核心领域中的每一个至少一门课程（生物催化、生物反应器和生物分离、分子生物学和遗传学）; B）参加跨学科研讨会“生物催化展望”; c）参加生物催化研讨会方案; d）参加题为“学术诚信原则”的课程; e）在工业或政府实验室实习; f）在年度生物催化和生物处理会议上展示研究成果。需要为8名博士前学员提供支助。学员在研究生院的第二年进入该计划，并可续签长达两年的支持。培训项目由项目总监（丹尼尔M. Quinn）和联合主任（Amnon Kohen），在生物催化和生物加工中心（CBB）的工作人员协助下，并听取了协调委员会的建议。协调委员会还担任CBB的执行委员会，从而确保培训计划和国家资助的中心之间的密切协调。培训计划的重点是招募和培训多元化的学员。这一重点不仅满足了国家的需要，而且为受训人员提供了更具包容性的教育经验。 公共卫生相关性：参与的教师实验室为学员提供了广泛的生物医学科学研究机会。其中包括对化学转化的环境友好的生物催化过程的研究，新抗生素和阿尔茨海默病药物的开发，生物传感器的开发，新抗癌药物的合成和评估，以及基因传递的新方法。培训计划课程提高了学员对生物医学和生物工程科学的理解，并为研究的道德行为提供指导。

DESCRIPTION (provided by applicant): This application requests continued support for a Predoctoral Training Program in Biotechnology that was first funded in 1990. Twenty nine participating faculty are drawn from six departments and four colleges: Chemistry, (College of Liberal Arts & Sciences); Biochemistry, Microbiology (College of Medicine); Civil & Environmental Engineering, Chemical & Biochemical Engineering (College of Engineering); Medicinal and Natural Products Chemistry (College of Pharmacy). This diverse faculty provides trainees with disciplinary backgrounds that lead to the Ph.D. degree in their respective departments. The following required activities provide the interdisciplinary background appropriate for biotechnology-oriented careers: a) at least one course in each of the three core areas of biotechnology (Biocatalysis, Bioreactors & Bioseparations, Molecular Biology & Genetics); b) participation in the interdisciplinary seminar "Perspectives in Biocatalysis"; c) participation in the Biocatalysis Seminar Program; d) take a course entitled "Principles of Scholarly Integrity"; e) serve an internship in an industrial or government laboratory; f) present research in the annual Biocatalysis and Bioprocessing Conference. Support for 8 predoctoral trainees is requested. Trainees enter the program in their second year of graduate school, and may be renewed for up to two years of support. The Training Program is administered by the Program Director (Daniel M. Quinn) and co-Director (Amnon Kohen), with staff assistance from the Center for Biocatalysis and Bioprocessing (CBB) and the advice of the Coordinating Committee. The Coordinating Committee also serves as the Executive Committee of the CBB, thereby insuring close coordination between the Training Program and the state-funded Center. An emphasis of the Training Program is the recruitment and training of a diverse cohort of trainees. This emphasis not only addresses national needs but also provides a more inclusive educational experience for the trainees. PUBLIC HEALTH RELEVANCE: Participating faculty laboratories provide trainees with a wide range of research opportunities in the biomedical sciences. Among these are investigations of environmentally friendly biocatalytic processes for chemical transformations, development of new antibiotics and Alzheimer's disease agents, biosensor development, synthesis and evaluation of new anticancer drugs, and new approaches to gene delivery. Training Program coursework enhances trainee understanding of biomedical and bioengineering sciences, and provides guidance in the ethical conduct of research.