Diabetes Research and Training Center

概述（由申请人提供）：该申请是为了继续阿尔伯特爱因斯坦医学院的糖尿病研究和培训中心（DRTC），以支持糖尿病治疗和治愈的科学知识的发现，应用和转化。爱因斯坦DRTC的作用是：1)加强糖尿病研究、教育和培训；Ii)吸引、指导和留住研究人员；iii)提供最先进的核心服务，使研究生产力最大化；4)促进跨学科合作，5)促进科学发现从实验室到临床和社区的转化，特别是在服务不足和少数民族人群中。为了实现这些目标，我们要求支持一个全面负责管理、整合和促进研究和培训的行政部门。该组成部分将监督研究基地、生物医学和预防与控制核心、浓缩和试点与可行性研究项目。自上次申请以来，爱因斯坦DRTC通过新的领导和机构承诺，扩大了教师研究基地，扩展和开发了新的核心功能，并加强了浓缩和试点与可行性计划。特别是，在过去的16个月里，我们已经招募了10名新的爱因斯坦DRTC教员，根据他们新的糖尿病研究重点，任命了4名现有的爱因斯坦高级教员作为DRTC的成员，并为纽约其他机构的8名教员以及哥伦比亚大学drc的成员提供了爱因斯坦DRTC的全部教员资格。四个新的尖端生物医学核心，补充和增加了两个现有的爱因斯坦DRTC核心和其他机构核心已经提供的服务。DRTC生物医学核心包括：1)动物生理学；2)稳定同位素与代谢组学；3)激素测定；4)分析成像；5)流式细胞术；6)表观基因组学。预防和控制（P&C）部分也扩大了其行为、卫生服务和流行病学教员的研究基础，并建立了三个职能单位，包括：1)临床研究方法；2)行为干预/评价方法论；3)社会环境研究方法论。我们继续我们杰出的试点和可行性研究计划，通过该计划支持基础，临床和行为研究的新举措。爱因斯坦DRTC浓缩计划继续邀请杰出的演讲者，与西奈山医学院举行视频会议和共同举办研讨会，每周举办培训糖尿病研讨会，并提供核心教育研讨会和培训场所。

DESCRIPTION, OVERALL (provided by applicant): This application is to continue Albert Einstein College of Medicine's Diabetes Research and Training Center (DRTC) in order to support the discovery, application and translation of scientific knowledge for the treatment and cure of diabetes. The Einstein DRTC serves as a nexus to i) enhance diabetes research, education and training; ii) to attract, mentor and retain research investigators; iii) provide state-of-the-art Core services to maximize research productivity; iv) foster interdisciplinary collaborations, and v) to promote the translation of scientific findings from the bench to bedside and community, especially in underserved and minority populations. To accomplish these goals, we are requesting support for an administrative component with overall responsibility for management, integration and promotion of research and training. This component will supervise the Research Base, Biomedical and Prevention & Control Cores, the Enrichment and Pilot & Feasibility Study Programs. Since the previous application, the Einstein DRTC, through new leadership and Institutional commitment, has expanded the faculty Research Base, expanded and developed new Core functions and enhanced the Enrichment and Pilot & Feasibility Programs. In particular, over the past 16 months we have recruited 10 new Einstein DRTC faculty, appointed 4 existing senior Einstein faculty as members of the DRTC, based upon their new diabetes research focus, and provided full Einstein DRTC faculty membership to 8 faculty at other New York institutions as well as to the members of the Columbia DERC. Four new cutting-edge Biomedical Cores that complement and add to the services already provided by two existing Einstein DRTC cores and the other Institutional cores. The DRTC Biomedical Cores include, 1) Animal Physiology; 2) Stable Isotope & Metabolomics; 3) Hormone Assay; 4) Analytical Imaging; 5) Flow Cytometry; and 6) Epigenomics. The Prevention and Control (P&C) component has also expanded its research base of behavioral, health services, and epidemiological faculty and has established three functional units that include 1) Clinical Research Methodology; 2) Behavioral Intervention/Evaluation Methodology and 3) Social-Environment Research Methodology. We have continued our outstanding Pilot & Feasibility Study Program through which new initiatives in basic, clinical, and behavioral research are supported. The Einstein DRTC Enrichment program has continued to host outstanding speakers, to videoconference and co-host seminars with Mount Sinai Medical School, to have weekly trainee Diabetes Workshop presentations and to provide Core educational workshops and training venues.