Training Program in Cardiovascular Sciences

描述(由申请人提供)： 这是一个新的Ruth L.Kirschstein机构国家研究服务奖(T32)的申请书，题为心血管科学培训计划。该计划旨在为非常有前途的内科科学家和博士提供经过密切指导的多学科博士后研究培训，并为他们作为独立心血管研究人员的职业生涯做好准备。我们启动这一计划是为了满足越来越多的有才华的候选人的需求，他们希望为最终改善美国和世界心血管健康的研究密集型职业做好准备。在过去的七年里，纽约大学的高级心血管培训环境得到了极大的改善。我们招募了从事心血管生物学和疾病基础研究的功勋卓著的教员。同时，我们吸引了一批优秀的新教师，他们拥有强大的临床研究计划，研究心血管疾病的机制和治疗，以及医疗保健的提供和有效性，特别是与纽约市健康和医院公司合作，在服务不足的人群中。从这个人才团队中，我们组建了一支由11名初级导师和13名联合导师组成的培训教师队伍，他们被组织成三个特别强大的集群：(1)心肌/离子通道生物学和疾病；(2)血管生物学和疾病；以及(3)临床研究。这项拟议的计划有大量的机构支持，每年将资助四名实习生，大多数人是在完成我们ACGME批准的心脏病学奖学金的临床部分后进入该计划的。所有学员将完成为期两年的培训计划，其中包括：(1)强调研究工具、职业发展以及生物医学研究与临床护理之间的接口的教学学核心计划；(2)密集的、多学科的研究项目；以及(3)个性化的、基于团队的指导计划。我们相信，我们项目的毕业生将从事独立的研究工作，并在美国和其他地方加强心血管健康。

DESCRIPTION (provided by applicant): This is an application for a new Ruth L. Kirschstein Institutional National Research Service Award (T32), entitled Training Program in Cardiovascular Sciences. The program is designed to provide closely mentored, multidisciplinary postdoctoral research training to highly promising physician-scientists and PhDs and prepare them for careers as independent cardiovascular investigators. We embark upon this program to meet the needs of a growing pool of talented candidates who wish to prepare themselves for research- intensive careers that will ultimately improve cardiovascular health in the United States and the world. The environment for advanced cardiovascular training at NYU has dramatically strengthened during the past seven years. We have recruited highly meritorious faculty investigators pursuing fundamental studies of cardiovascular biology and disease. In parallel, we have attracted a number of outstanding new faculty members with robust clinical research programs investigating mechanisms and therapy of cardiovascular disease, as well as healthcare delivery and effectiveness, particularly among the underserved in partnership with the New York City Health and Hospitals Corporation. From this talented group we have assembled a training faculty of eleven primary mentors and thirteen associated mentors organized into three major clusters of particular strength: (1) Myocardial/lon Channel Biology and Disease; (2) Vascular Biology and Disease; and (3) Clinical Research. The proposed program, which has substantial institutional support, will fund four trainees each year, most entering the program after completing the clinical portion of our ACGME- approved cardiology fellowship. All trainees will complete a two-year training program that includes: (1) a core program of didactics that stresses research tools, career development and the interface between biomedical research and clinical care; (2) an intensive, multi-disciplinary research project; and (3) a personalized, team-based mentoring program. We are confident that graduates of our program will pursue independent investigative careers and enhance cardiovascular health in the US and elsewhere.