IMAGING RESEARCH CORE

成像研究核心设施为研究人员提供最先进的设施和服务 活体成像。该设施为癌症研究人员提供了广泛的成像研究基础设施和 -15放射学和生物医学工程领域的成像专业知识，以增强和扩展他们的 正在进行的研究工作。专用的小动物成像系统的出现允许集成 活体生理测量和结构和细胞活动的微观测量。这个 协作、多学科的方法为阐明该复杂结构提供了丰富的新信息 基因操纵动物模型的结构、遗传学、复制和功能之间的关系 已广泛用于癌症研究的疾病，其基础是细胞/分子水平 理解。影像研究核心设施是病例成像中心的核心部分 这项研究涵盖了凯斯/UHC更广泛的成像研究计划的所有方面。 这包括分子成像、小动物成像和临床成像推力。许多这样的推力 与Case综合癌症中心(Case CCC)直接相关。影像研究的核心 介绍了该机构的分子和小动物成像服务、技术和研究计划 在下面详细介绍。临床影像研究计划在计划7中有更详细的描述： 发展治疗学提案。

The Imaging Research Core Facility provides researchers with the state-of-the art facilities and services for in vivo imaging. The facility provides cancer researchers its extensive imaging research infrastructure and expertise of -15 imaging faculty in Radiology and Biomedical Engineering to enhance and expand their ongoing research efforts. The advent of dedicated small animal imaging systems allows the integration of in vivo physiologic measurements with microscopic measurements of structural and cellular activities. The collaborative, multi-disciplinary approach provides a wealth of new information in elucidating the complex relationship between structure, genetics, replication, and function in genetically manipulated animal models of disease that have been used widely in cancer research with grounding in cellular/molecular-level understanding. The Imaging Research Core Facility is the centerpiece of the Case Center for Imaging Research which encompasses all aspects of the much broader imaging research program at Case/UHC. This includes molecular imaging, small animal imaging, and clinical imaging thrusts. Many of these thrusts are directly tied to the Case Comprehensive Cancer Center (Case CCC). The Imaging Research Core Facility's molecular and small animal imaging services, technologies, and research programs are described in detail below. Clinical imaging research programs are described in more detail in the Program 7: Developmental Therapeutics proposal.