CARBOHYDRATE METABOLISM IMPAIRMENTS IN CHRONIC HUMAN SPINAL CORD INJURY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 随着脊髓损伤(SCI)患者年龄的增长，他们更有可能出现健康问题，就像其他人一样。然而，脊髓损伤增加了某些问题的风险。本研究项目将重点研究脊髓损伤后血糖的控制。血液中的糖是身体的重要能量来源。血液中的糖分过多被称为高血糖，而血液中的糖分不足被称为低血糖。在健康的条件下，血液中的糖量会自动调节，从而保持稳定的水平。然而，在脊髓损伤后，这种自动调节被破坏。血糖过高或过低的可能性都会增加。随着时间的推移，血糖过高会导致糖尿病的发展。在恰恰相反的情况下，患有脊髓损伤的人可能会开始经历更频繁的血糖过低发作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. As people with spinal cord injuries (SCI) get older they become more likely to develop health problems, just like everyone else. However, SCI increases the risk of certain problems. This research project will focus on the control of blood sugar after SCI. Sugar in the blood is the important source of energy for the body. Too much sugar in the blood is known as hyperglycemia and not enough sugar in the blood is known as hypoglycemia. Under healthy conditions, the amount of sugar in the blood is automatically regulated so that a steady level is maintained. After SCI, however, this automatic regulation is damaged. The likelihood of experiencing too much or too little blood sugar is increased. Over time, having too much blood sugar can lead to the development of diabetes. In just the opposite situation, individuals with SCI can begin to experience more frequent episodes of too little blood sugar.