FUNCTIONAL MRI IN HUMANS AT 7 TESLA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目前，绝大多数磁共振成像和功能成像研究是在1.5或3.0特斯拉的相对较低磁场下进行的。然而，理论考虑和实验证据表明，图像的信噪比、功能成像对比度和空间特异度与磁场强度有根本的依赖关系。这项建议的总体目标是发展功能磁共振成像和磁共振成像技术，用于在强磁场(7T和9.4T)下进行全脑采集。为了实现这一目标，将首次在9.4特斯拉的超高磁场下进行人体fMRI/MRI研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Currently, the vast majority of magnetic resonance imaging and functional imaging studies are conducted at relatively low magnetic fields of 1.5 or 3.0 Tesla. However, theoretical considerations as well as experimental evidence have suggested that there is a fundamental dependence of image signal to noise ratios, functional imaging contrast and spatial specificity on the magnetic field strength. The general aim of this proposal is development of fMRI and MRI techniques for whole brain acquisitions at high magnetic fields (7 T & 9.4 T). In achieving this aim, fMRI/MRI studies will be conducted at the ultra-high magnetic field of 9.4 Tesla for the first time in humans.