FUNCTIONAL MRI IN HUMANS AT 7 TESLA

7 特斯拉时的人体功能 MRI

• 批准号: 8362847
• 负责人: ESSA YACOUB
• 金额: $ 3.03万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362847
• 关键词: Brain; Dependence; Development; Functional Imaging; Functional Magnetic Resonance Imaging; Funding; Grant; Human; Image; Magnetic Resonance Imaging; NMR Spectroscopy; National Center for Research Resources; Noise; Principal Investigator; Research; Research Infrastructure; Resources; Signal Transduction; Source; Specificity; Techniques; Time; United States National Institutes of Health; cost; magnetic field

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Currently, the vast majority of magnetic resonance imaging and functional imaging studies are conducted at relatively low magnetic fields of 1.5 or 3.0 Tesla. However, theoretical considerations as well as experimental evidence have suggested that there is a fundamental dependence of image signal to noise ratios, functional imaging contrast and spatial specificity on the magnetic field strength. The general aim of this proposal is development of fMRI and MRI techniques for whole brain acquisitions at high magnetic fields (7 T & 9.4 T). In achieving this aim, fMRI/MRI studies will be conducted at the ultra-high magnetic field of 9.4 Tesla for the first time in humans.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 目前，绝大多数磁共振成像和功能成像研究都是在 1.5 或 3.0 特斯拉的相对较低磁场下进行的。然而，理论考虑和实验证据表明，图像信噪比、功能成像对比度和空间特异性对磁场强度存在根本依赖性。该提案的总体目标是开发用于高磁场（7 T 和 9.4 T）下全脑采集的 fMRI 和 MRI 技术。为了实现这一目标，功能磁共振成像/磁共振成像研究将首次在人类身上进行 9.4 特斯拉的超高磁场。