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中文摘要
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描述(由申请者提供):2011年AUA基金会/SBUR基础科学研讨会将于2011年AUA年会在华盛顿举行,定于2011年5月13日(星期五)下午1:00至6:00举行。会议得益于新的研究人员和成功的高级研究人员在舒适、非正式的环境中的协同作用。在这次会议上讨论和分享的信息有望有助于将临床研究转化为实际应用。它还打算作为一个论坛,让年轻的研究人员有机会与干细胞生物学领域的领导人见面和互动。通过了解干细胞及其在泌尿系统疾病中的潜在作用,初级研究人员将处于更好的地位,以评估干细胞生物学是否可以纳入他们自己的研究项目。会议期间建立的联系预计将促进研究合作,并将这一令人兴奋的研究领域推广给下一代研究人员。会议的联席主席兼首席调查员周旺博士是SBUR的当选主席。其他联席主席,医学博士David Jarrard和博士Simon Hayward是SBUR执行委员会成员和基础科学和卫生服务研究领域的领导者。会议由一次主题演讲、两次主要会议和一次小组讨论组成。普渡大学癌症中心主任、SBUR创始人兼第一任总裁Timothy Ratliff博士应邀就基础科学对泌尿外科领域的重要性发表开幕词。主旨演讲将提出这样一个问题:“干细胞是什么?我们对它们了解多少?”主要课程是“干细胞生物学”和“干细胞治疗”。项目中期休息时间将为年轻研究人员提供与教职员工和资深参与者互动的机会。AUA及其附属专业学会的领导人以及来自国家卫生研究院、国家老龄研究所、国家糖尿病和消化与肾脏疾病研究所以及国家癌症研究所的科学和项目官员将被邀请参加。这次会议将促进新的泌尿外科研究人员的发展和未来的成功,并为合作研究努力奠定基础。 公共卫生意义:2011年,美国泌尿协会(AUA)基金会和基础泌尿研究学会(SBUR)将举办一场名为“干细胞在泌尿系统疾病中”的基础科学研讨会。AUA基金会和SBUR的这一联合努力旨在对一个重要的主题领域进行严格和深入的讨论,该主题领域将吸引该领域的领导者、领先的泌尿科研究人员、临床泌尿科医生和初级调查人员参加AUA年会,并将推动泌尿学研究的进步。这也可能为干细胞生物学家和泌尿科研究人员之间的合作带来新的机会。这些相互作用有望促进将干细胞生物学整合到各种泌尿学研究项目中,并最终导致实验室发现转化为临床环境,反之亦然。这次研讨会将增进泌尿科研究界对干细胞生物学的了解。它还将对干细胞生物学在泌尿外科研究和临床实践中的当前和未来应用进行全球评估。
英文摘要
DESCRIPTION (provided by applicant): The 2011 AUA Foundation/SBUR Basic Sciences Symposium will be held at the 2011 AUA Annual Meeting in Washington DC, and is scheduled for Friday, May 13, 2011 from 1:00 to 6:00 p.m. The conference benefits from the synergy of new investigators and successful senior researchers in a comfortable, informal setting. The information discussed and shared during this meeting is expected to assist in translating clinical research to practical application. It is also intended to serve as a forum where young investigators have the opportunity to meet and interact with leaders in the field of stem cell biology. By learning about stem cells and their potential roles in urological disease, junior investigators will be in better positions to assess whether stem cell biology can be incorporated into their own research projects. The connections made during the meeting are expected to stimulate research collaborations and promote this exciting area of research to the next generation of investigators. The co-chair and primary investigator for the meeting, Zhou Wang, PhD is the president-elect of the SBUR. The other co-chairs, David Jarrard, MD and Simon Hayward, PhD are members of the SBUR Executive Committee and leaders in the fields of basic science and health services research. The meeting is organized into a keynote lecture, two main sessions, and a panel discussion. Timothy Ratliff, PhD, Director of the Purdue University Cancer Center and SBUR founder and first president has been invited to deliver an opening address on the importance of basic science to the field of urology. The keynote address will pose the question, "What are Stem Cells and What Do We Know About Them?" The main sessions are "Biology of Stem Cells" and "Stem Cells for Therapy." A mid-program break will provide a networking opportunity for young investigators to interact with faculty and senior attendees. Leaders of the AUA and its affiliated specialty societies along with scientific and program officers from the National Institutes of Health National Institute of Aging, National Institute of Diabetes & Digestive & Kidney Diseases, and the National Cancer Institute will be invited to attend. This meeting will promote the development and future success of new urologic research investigators and establishing a foundation for collaborative research efforts. PUBLIC HEALTH RELEVANCE: In 2011, the American Urological Association (AUA) Foundation and the Society for Basic Urologic Research (SBUR) will offer a Basic Sciences Symposium, entitled "Stem Cells in Urologic Diseases". This joint effort between the AUA Foundation and the SBUR is intended to be a rigorous and in-depth discussion of an overarching topic area that will attract leaders in the field, leading urology researchers, clinical urologists and junior investigators to the AUA Annual Meeting and that will advance progress in urology research. This may also lead to new opportunities for collaborations between stem cell biologists and urological researchers. These interactions will hopefully facilitate the integration of stem cell biology into various urological research projects and eventually lead to the translation of laboratory bench findings into clinical settings and visa versa. This symposium will enhance the understanding of stem cell biology in the urological research community. It will also provide a global assessment on the current and future applications of stem cell biology in urological research and clinical practice.
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Structural and functional analysis of a novel class of androgen receptor antagonists
Role of E-Cadherin Down-Regulation in Prostatic Inflammation and Lower Urinary Tract Dysfunction
Targeting androgen receptor nuclear localization in prostate cancer
University of Pittsburgh O'Brien Cooperative Research Center Program
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