Albany 2011: The 17th Conversation

描述（由申请人提供）：奥尔巴尼2011年：第17次对话将于2011年6月14日至18日在纽约州立大学奥尔巴尼。当晚的主题演讲将由诺贝尔奖得主、哈佛大学的Jack Szostak发表，主题是自我复制系统的实验室合成和生命的起源。对话将涵盖结构生物学的以下领域：蛋白质：什么是新的，更新和最新的？蛋白质：Allostery，协同性和运动;蛋白质内无序蛋白质和神经变性;蛋白质进化;分子模拟中的断裂;进化：益生元合成;染色体-细胞核景观;人工DNA; DNA纳米技术; DNA-蛋白质相互作用;顺式调节模块; DNA损伤和修复;转录-复制碰撞。此外，还将庆祝大卫贝弗里奇，自1979年以来的组织委员会成员。 这些主题将由特邀讲座和海报讨论文件涵盖。共有83场讲座，55场由资深科学家主讲，28场由年轻研究人员主讲。青年研究人员（研究生、博士后研究员和初级教员）的讲座将根据提交海报展示的摘要进行选择。5.5在收到海报的摘要之前，专题讨论会将空出几个小时的时间，以便从摘要中选择大量的演讲。提交的海报数量将超过200张。在总共83场演讲中，至少有30场将由女科学家主讲。该计划将接纳来自20多个国家的约400名科学家。 公共卫生相关性：会议，如内在无序蛋白质和神经变性; DNA损伤和修复;顺式调节模块;染色体-细胞核景观;和DNA-蛋白质相互作用直接处理分子疾病，以及如何设计方法来治愈和管理它们。其余的主题着眼于医学生物化学基本领域的进展，这里的进展将对我们未来管理疾病（包括衰老和癌症）的方式产生深远的影响。

DESCRIPTION (provided by applicant): Albany 2011: The 17th Conversation will be held in June 14-18 2011 at the State Univ. of New York at Albany. The Keynote evening lecture will be delivered by Nobel Laureate Jack Szostak, Harvard, on the laboratory synthesis of self-replicating systems and the origin of life. The Conversation will cover the following areas of structural biology: Proteins: What is New, Newer and Newest? Proteins: Allostery, Cooperativity and Motion; Intrinsically Disordered Proteins and Neurodegeneration; Protein Evolution; Breakthroughs in Molecular Simulations; Evolution: Prebiotic Synthesis; Chromosomes - Landscape of the Cell Nucleus; Artificial DNA; DNA Nanotechnology; DNA-Protein Interactions; Cis-Regulatory Modules; DNA Damage and Repairs; Transcription-Replication Collisions. In addition there will be celebration of David Beveridge, a member of the Organizing Cmte since 1979. The subjects will be covered by invited lectures and poster discussion papers. There will be a total of 83 lectures, 55 by senior scientists and 28 by young researchers. Lectures by young researchers (graduate students, post-doctoral fellows and starting faculty) will be based on selection from abstracts submitted for poster presentation. 5.5 hours of the symposium time will be left vacant until abstracts for posters are received so that a significant number of lectures can be selected from the abstracts. The number of posters presented will be over 200. Out of a total of 83 talks, a minimum of 30 will be delivered by female scientists. The program will admit some 400 scientists from over 20 Nations. PUBLIC HEALTH RELEVANCE: Sessions such as Intrinsically Disordered Proteins and Neurodegeneration; DNA Damage and Repairs; Cis-Regulatory Modules; Chromosomes - Landscape of the Cell Nucleus; and DNA- Protein Interactions deal directly with molecular diseases, and how one devises approaches to cure and manage them. The remaining topics look at advances in fundamental areas of medical biochemistry, and progress here will have profound impact on the way we will manage disease, including aging and cancer, in the future.