Training Students in Biomedical Research in Hematology

描述（由申请人提供）：项目摘要本项目的目的是通过匹兹堡大学血液学生物医学研究项目为医学生提供培训机会。鉴于血液学中令人兴奋的分子发现以及缺乏经过充分多学科培训的医生科学家进行重要的转化研究，该项目的最终目标是让学生对学术血液学职业感兴趣。来自血液学/肿瘤学，血管生物学，分子生物学，药理学，凝血和血栓形成，输血医学，放射和外科肿瘤学以及匹兹堡大学流行病学等广泛学科的22名匹兹堡大学学术核心教师可提供广泛的基础和临床研究主题，研究人群和生物医学技术，临床和实验室空间，以执行这一项目，其具体目标是：（1）让医学生在培训早期接触学术血液学生物医学研究的相关性和兴奋性，特别是通过为期8周的指导研究项目，无论是实验室还是临床，拥有一个由学术临床医生和科学家组成的核心教师队伍。 (2)为学生提供研究基础方面的教学培训，包括批判性文献综述和分析思维的工具，以及对血液学基本原理的理解，作为进行科学合理和相关生物医学研究的基础。 (3)促进由知名学术医生和科学家对医学生进行研究概念和协作研究方面的指导和辅导培训，包括概念开发、研究设计、数据收集和分析、手稿准备和摘要演示，以便提供工具进行生物医学研究和学习第一手的学术研究职业知识。通过这种丰富，多样和跨学科的学术教师资源，我们建议通过指导研究经验，在他们大一后的夏天，医学生在研究的兴趣。

DESCRIPTION (provided by applicant): Project Summary The purpose of this project is to provide opportunities for medical student training through mentored biomedical research projects in hematology at the University of Pittsburgh. Given the exciting molecular discoveries in hematology and the shortage of physician scientists with sufficient multi-disciplinary training to carry out important translational research, the ultimate goal of this project is to interest students in careers in academic hematology. A total of 22 University of Pittsburgh academic core faculty members from the broad disciplines of hematology/oncology, vascular biology, molecular biology, pharmacology, coagulation and thrombosis, transfusion medicine, radiation and surgical oncology, and epidemiology at the University of Pittsburgh are available to provide a broad array of basic and clinical research topics, study populations, and biomedical techniques, clinical and laboratory space to carry out this project, the specific aims of which are: (1) To expose medical students early in their training to the relevance and excitement of biomedical research in academic hematology, specifically through 8-week mentored research projects, either bench or clinical, with a core faculty of established academic clinicians and scientists. (2) To provide didactic training for students in research fundamentals, including the tools for critical literature review and analytic thinking, and an understanding of the basic principles of hematology, to serve as the basis for the conduct of scientifically sound and relevant biomedical research. (3) To promote guided and mentored training of medical students, by established academic physicians and scientists, in research concepts and collaborative research, including concept development, study design, data collection and analysis, manuscript preparation, and abstract presentation, in order to provide the tools for performing biomedical research and learning first-hand about careers in academic research. Through this rich, diverse, and interdisciplinary academic faculty resource, we propose to interest medical students in research through mentored research experiences during the summer following their freshman year.