Research Training Program in Enviromental Toxilogy

描述（由申请人提供） 这是一个竞争性的延续申请，以更新环境毒理学研究培训计划。 该计划成立于2000年，旨在帮助招募新的科学家进入这一重要学科，该计划教育生殖，发育和内分泌毒理学的博士前和博士后学员。在毒理学的这些方面培训学生和博士后研究员的需求与10年前首次构思培训计划时一样紧迫。 作为内分泌干扰物的环境化学品仍然是环境健康关切的主要问题。该计划结合了伊利诺伊大学校园内两个长期公认的卓越研究领域，环境毒理学和生殖生物学，研究人员可以在伊利诺伊大学校园内的一些最亮的明星中计算他们的导师。自上次提交以来，几位杰出的新导师加入了该计划（Flaws，Hofmann），本次更新申请中增加了两位导师（Boppart，Freund），共有来自七个部门的15位导师（动物科学，生物工程，化学，作物科学，食品科学和人类营养，分子和综合生理学以及兽医生物科学）。这些教师目前共有40多个联邦资助的研究赠款，每年直接费用超过900万美元。导师们正在研究内分泌活性化学品使用广泛的多学科视角。在分子，细胞，整个动物和人类健康水平上工作的实验室之间的合作为学员提供了直接观察和参与转化研究的独特机会。学员的选择是基于学术成就，拟议的研究计划的目标和毒理学的承诺的相关性。优先考虑在研究生学习的第一年或第二年的博士前实习生。该计划提供了广泛的毒理学研究生水平的课程。 除了他们的部门要求，所有博士前学员采取基本毒理学，系统毒理学和至少一个其他先进的毒理学课程与他们的研究领域。 博士后学员进行独立的毒理学研究。所有学员都必须参加每周一次的毒理学研究研讨会、职业发展讲习班、毒理学杂志俱乐部和毒理学研究伦理课程。还要求受训者在研讨会上介绍他们的研究，并大力鼓励他们在国家会议上介绍他们的研究。 调查人员在从代表性不足的群体中招募和留住合格学生方面有着良好的记录，我们将继续并扩大这些努力。 相关性：该培训计划将培养博士前和博士后学生成为下一代内分泌，发育和生殖毒理学研究科学家，毒理学的子学科与人类健康直接相关。

DESCRIPTION (provided by applicant) This is a competing continuation application to renew the Research Training Program in Environmental Toxicology. Established in 2000 to help recruit new scientists into this important discipline, the Program educates pre- and postdoctoral trainees in reproductive, developmental and endocrine toxicology. The need to train students and postdoctoral fellows in these aspects of toxicology is every bit as urgent today as it was 10 years ago when the training program was first conceived. Environmental chemicals that act as endocrine disrupters continue to dominate environmental health concerns. The program unites two long recognized areas of research excellence on the University of Illinois campus, environmental toxicology and reproductive biology, and the investigators can count among their preceptors some of the brightest stars on the University of Illinois campus. Several outstanding new preceptors have joined the Program since the last submission (Flaws, Hofmann) and two additional preceptors are added in this renewal application (Boppart, Freund) resulting in a total of 15 preceptors from seven departments (Animal Sciences, Bioengineering, Chemistry, Crop Sciences, Food Science and Human Nutrition, Molecular and Integrative Physiology and Veterinary Biosciences). Together these faculty currently have over 40 federally funded research grants totaling more than $9 million dollars per year direct costs. The preceptors are researching endocrine active chemicals using a broad multidisciplinary perspective. Collaborations among laboratories working at the molecular, cellular, whole animal and human health levels provide trainees with the unique opportunity to directly observe and participate in translational research. Selection of trainees is based on academic success, relevance of proposed research to Program goals and commitment to toxicology. Preference is given to pre-doctoral trainees in their first or second year of graduate study. The Program offers a broad range of graduate level courses in toxicology. In addition to their departmental requirements, all pre-doctoral trainees take basic toxicology, systems toxicology and at least one other advanced toxicology course related to their field of study. Postdoctoral trainees conduct independent research in toxicology. All trainees are required to attend weekly toxicology research seminars, career development workshops, a toxicology journal club and a course on research ethics in toxicology. Trainees are also required to present their research in the seminar and strongly encouraged to present their research at national meetings. The investigators have a strong record of recruiting and retaining qualified students from underrepresented groups and we will continue and expand these efforts. Relevance: This Training Program will train pre- and postdoctoral students to become the next generation of research scientists in endocrine, developmental and reproductive toxicology, subdisciplines of toxicology that are directly relevant to human health.