COLUMBIA CENTER FOR HEALTH OF URBAN MINORITIES (CHUM)

这个应用程序代表了我们现有的NCMHD P60卓越中心，哥伦比亚城市少数民族健康中心（CHUM）的延续和进一步发展。在前三年的成功努力的基础上，我们建议将CHUM发展成为一个多学科的卓越中心，密切关注心血管疾病和糖尿病等NCMHD重点领域的研究。我们计划开展三个研究项目，旨在为改善加勒比拉丁裔少数民族的健康状况创造新知识。第一个项目是一项随机对照试验（RCT），在控制不良的拉丁裔糖尿病患者中进行，以检验基于社区的社区卫生工作者干预在改善血糖控制方面的有效性，并将血压和胆固醇作为次要结果。第二个项目是一项前瞻性研究，研究血糖控制不良对糖尿病患者认知功能的长期影响。第三个项目也是一项随机对照试验，将评估以社区为基础的综合治疗性生活方式干预的有效性，该干预包括小组会议和关于血压控制的动机访谈。该应用程序包括一个行政和研究核心，提供必要的行政、方法、统计和数据管理基础设施，以开展这三个主题相关的研究项目。所有三个项目都将在本地社区进行，而在港大第一阶段成立的规划委员会将继续作为社区对港大项目的整体方向、形式和执行提供意见的正式场所。此外，这两项随机对照试验都建立在CHUM社区核心建立的社区伙伴关系基础上，并将社区组织作为研究的组成部分。最后，中大将透过已建立的伙伴关系，以及成功获得其他来源的支持，继续为初级教师、博士后学员、研究员和本科生提供培训机会。

This application represents a continuation and further development of our existing NCMHD P60 Center of Excellence, the Columbia Center for the Health of Urban Minorities (CHUM). Building on the successful efforts of CHUM's first three years, we propose to develop CHUM into a multidisciplinary Center of excellence tightly focused on research in the NCMHD priority areas of cardiovascular disease and diabetes. We plan to conduct three research projects aimed at generating new knowledge for improving minority health among Caribbean Latinos. The first project is a randomized controlled trial (RCT) in poorly controlled Latino diabetics to examine the effectiveness of a community based Community Health Worker intervention at improving glycemic control and includes blood pressure and cholesterol as secondary outcomes. The second project is a prospective study examining the long-term consequences of poor glycemic control on cognitive function among diabetics. The third project, also an RCT, will evaluate the effectiveness of a community-based comprehensive therapeutic lifestyle intervention that includes group sessions and motivational interviewing on blood pressure control. The application includes an administrative and research core providing the requisite administrative, methodological, and statistical and data management infrastructure to carry out these three thematically linked research projects. All three projects will be conducted in our local community and the Planning Council established in the 1st phase of CHUM will continue to serve as the formal venue for community input into the overall direction, shape and execution of the CHUM project. Further, both RCTs build on the community partnerships established by CHUM's Community core and include community based organizations as integral members of the research. Lastly, through CHUM's established partnerships and successful efforts at obtaining support from other sources, CHUM will continue to provide training opportunities for junior faculty, post-doctoral trainees, fellows and undergraduate students.