Research and Mentoring on Alcohol Clinical and Human Laboratory Research

描述（由申请人提供）：这是一个高级科学家研究和导师奖（K05）申请斯蒂芬A。Maisto博士本申请的主要目标是推进我在以下方面的研究计划：（1）酒精和其他药物评估和治疗研究方法，（2）酒精治疗结果，过程，临床过程和复发，以及（3）人类酒精挑战研究，继续探索统计方法和纵向研究技术，可用于推进有关酒精治疗结果的知识，治疗相关变化的机制，酒精治疗的临床过程和复发，并增加我在指导初级研究人员和科学教育方面的成功。K05奖将使我能够在高水平的活动中追求这些主要目标，这是我目前的K02奖期间的特点，该奖项将于2007年8月31日结束。在K05奖期间，我建议继续我在上述研究领域的研究计划，该计划以锡拉丘兹大学为基础，并与纽约州立大学北部医科大学（锡拉丘兹，纽约州），弗吉尼亚州北部医学网络和美国其他机构的同事合作。我最初的指导计划，使可行的K05奖包括两个博士学位。2 MD学员，我打算在K05奖励期内每年保持4名初级研究员学员。此外，我的计划是在整个K05奖期间，以博士后研究员或精神病学和家庭医学的住院医师为中心开展科学教育活动。

DESCRIPTION (provided by applicant): This is a Senior Scientist Research and Mentorship Award (K05) application for Stephen A. Maisto, Ph.D. The primary goals of this application are to advance my research programs in (1) alcohol and other drug assessment and treatment research methods, (2) alcohol treatment outcomes, process, clinical course, and relapse, and (3) human alcohol challenge research, to continue to explore statistical methods and techniques of longitudinal research that may be applied to advance knowledge about alcohol treatment outcomes, mechanisms of treatment-related change, alcohol treatment clinical course, and relapse, and to add to my success in mentoring junior investigators and in science education. The K05 award would allow me to pursue these primary aims at the high level of activity that has characterized the period of my current K02 award, which ends on 8/31/07. During the K05 award period, I propose to continue my research program in the research areas noted above and that is based in Syracuse University and in collaboration with colleagues at SUNY Upstate Medical University (Syracuse, NY), the VA Medical Upstate NY Network, and at other institutions in the US. My initial Mentoring Plan made feasible by the K05 award includes two Ph.D. and 2 M.D. mentees, and I intend to maintain a cohort of 4 junior investigator mentees for each year of the K05 award period. In addition, my plan is to engage in science education activities centering on postdoctoral fellows or residents in psychiatry and family medicine throughout the K05 award period.