ADVANCE AND SUPPORT THE RESEARCH INFRASTRUCTURE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 在亨特学院基因结构和功能研究中心的RCMI支持的核心共享研究设施提供必要的服务，以支持我们的科学家的一流研究。我们必须通过不断更新管理人员和用户的设备和专业知识来提高设施的实力。这些设施也使我们能够竞争顶尖的科学家，高素质的研究生和博士后研究人员谁有助于我们的研究成果。一个研究人员成功竞争外部资金的环境对我们的总体目标至关重要，随着新的和计划中的设施的增加，我们将能够更好地解决美国的健康差距问题。在下一个赠款期间，我们计划雇用必要的人员，并升级以下设施的设备：生物成像，动物护理，基因组学，Internet2和基因中心局域网（LAN）。我们的计划包括改善这些核心共享研究设施以及荧光激活细胞分选（FACS），核磁共振（NMR）和X射线衍射设施。 这些改进需要以下方面：（a）用赠款和用户费支持服务合同;（B）通过高级培训、继续教育、外部合作和专业认证，提高设施管理人员的技能;（c）更新标准作业程序、记录保存、手册和网站。 改善我们的核心设施将有助于我们最大限度地提高我们的科学产出，实现RCMI计划的目标。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The RCMI-supported core shared research facilities at the Center for Study of Gene Structure and Function at Hunter College provide essential services to support the first-class research of our scientists. It is imperative that we improve the strengths of the facilities by constantly updating the equipment and expertise of the managers and users. The facilities also allow us to compete for topnotch scientists, highly qualified graduate students and post-doctoral researchers who contribute to our research output. An environment where researchers compete successfully for outside funding is critical to our overall aims, and with the addition of new and planned facilities we will be able to better address the problem of health disparities in the United States. In the next grant period, we plan to hire essential personnel and to upgrade the equipment in the following facilities: Bioimaging, Animal Care, Genomics, Internet2 and the Gene Center Local Area Network (LAN). Our plans include improving these core shared research facilities as well as the Fluorescence Activated Cell Sorting (FACS), the Nuclear Magnetic Resonance (NMR) and the X-Ray Diffraction Facilities. These improvements require the following: (a) supporting service contracts with grant funds and users' fees; (b) upgrading the skills of facilities' managers through advanced training, continuing education, external collaborations and professional certifications; and (c) upgrading standard operating procedures, record-keeping, manuals, and websites. Improving our core facilities will help us to maximize our scientific output and attain the goals of the RCMI Program.