South Dakota Biomedical Research Infrastructure Network

描述(由申请者提供)：南达科他州生物医学研究基础设施网络(SD Brin)，由南达科他州大学桑福德医学院(U.S.SSOM)在南达科他州弗米尔市主办，是IDEA卓越生物医学研究网络(INBRE)计划的SD组成部分，由NIH/NCRR机构发展奖(IDEA)计划资助。该INBRE第二阶段提案是在INBRE第一阶段所获得的见解和改进的基础上发展而来的。SD INBRE第二阶段的两个主要目标是相同目标的扩展，这为第一阶段提供了重点。SD Brin设想在SD内部建立一个强大的跨学科协作网络，以增强细胞生物学和细胞生长控制方面的基础生物医学研究能力。这一愿景强调在主办机构和主要是本科生机构(PUI)合作伙伴的蛋白质组和基因组学。SD的INBRE的第二阶段目标是：1)发展SD在细胞生物学和细胞生长控制方面的研究能力，重点是蛋白质组和基因组学：a)通过对初级教员的指导，提高蛋白质组和基因组学方面的研究能力和关键研究人员的数量，b)为整个SD(和其他理想国家)的研究人员保持专业人员的蛋白质组学、基因组学、生物信息学和DNA测序和基因分型核心设施，以及c)在基础生物医学科学和生物信息学方面提供更多的研究生培训和研究支持。2)为生物医学和生物信息学的本科生和研究生课程开发人力资源，灌输研究文化，并通过以下方式为南达科他州以本科为主的机构和部落学院的学生提供对生物医学研究感兴趣的渠道：a)为参与机构的初级研究人员和教职员工提供研究支持和指导，b)为参与机构的学生提供机会和了解尖端科学研究，c)向本科生介绍生物医学科学和生物信息学的研究生课程和未来的职业生涯，以及d)加强部落学院的科学教育和研究能力，为进一步教育和从事科学研究提供机会。 公共卫生相关性(由申请者提供)：SD Brin正在与以本科为主的机构合作，并通过资助主办机构的核心资源，为生物医学研究开发和支持全州范围的跨学科网络基础设施。整个SD的教职员工和学生在规划和进行生物医学研究方面都得到了支持。

DESCRIPTION (provided by applicant): South Dakota Biomedical Research Infrastructure Network (SD BRIN), hosted by Sanford School of Medicine of University of South Dakota (USD SSOM) in Vermillion, SD, is the SD component of IDeA Networks of Biomedical Research Excellence (INBRE) program funded by NIH/NCRR Institutional Development Award (IDeA) program. This Phase II proposal for INBRE evolved from insights gained and enhancements made during Phase I of INBRE. Two main goals for SD INBRE Phase II are extensions of the same goals which provided a focus for Phase I. SD BRIN envisions a robust interdisciplinary collaborative network within SD to enhance basic biomedical research capabilities in cell biology and control of cell growth. This vision emphasizes proteomics and genomics at the host institution and predominantly undergraduate institutional (PUI) partners. Phase II goals for INBRE in SD are to: 1) Develop research capacity of SD in cell biology and the control of cell growth with emphasis on proteomics and genomics by: a) enhancing research capacity and critical mass of investigators in proteomics and genomics via mentoring of junior faculty members, b) maintaining professionally staffed proteomics, genomics, bioinformatics, and DNA sequencing and genotyping core facilities for investigators throughout S.D. (and other IDeA states), and c) providing increased graduate training and research support in basic biomedical sciences and bioinformatics. 2) Develop human resources for undergraduate and graduate programs in the biomedical sciences and bioinformatics, instill a culture of research, and provide a pipeline for students interested in biomedical research at South Dakota's predominantly undergraduate institutions and tribal colleges by: a) providing research support and mentoring for junior investigators and faculty from participating institutions, b) providing opportunities for, and understanding of, cutting-edge scientific research for students at participating institutions, c) introducing undergraduates to graduate programs and future careers in biomedical sciences and bioinformatics, and d) enhancing science education and research capabilities at tribal colleges, providing opportunities for further education and careers in science and research. PUBLIC HEALTH RELEVANCE (provided by applicant): SD BRIN is developing and supporting a state-wide interdisciplinary network infrastructure for biomedical research by partnering with predominantly undergraduate institutions and by funding core resources at the host institution. Faculty and students throughout SD are supported in planning and conducting biomedical research.