CHARACTERIZATION OF BLOOD FLOW IN DENTAL PULP

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 牙周病：牙髓的特征，加州大学欧文分校的Petra Wilder-Smith著 监测牙髓活力的能力对于准确的诊断和最佳的治疗计划至关重要。目前，临床上还没有准确的方法来评估牙髓的健康状况和治疗效果。这项研究的目的是开发和验证一种非侵入性测量牙髓血流的技术。体外研究表明，使用633 nm HeNe激光的激光散斑成像可以检测牙髓腔内的血流值。在牙髓中检测和半定量不同流速的能力已经被清楚地证明。数据表明，在较高的流速下，散斑流量值较高。我们目前正在使用牙科LSI原型仪器进行活体测量

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Periodontal disease: Characterization of dental pulp, with Petra Wilder-Smith, UC-Irvine The ability to monitor pulpal vitality is crucial for accurate diagnosis and optimal treatment planning. Currently, there exists no accurate means of clinically assessing pulpal health and treatment response. The aim of this study is to develop and validate a non-invasive technique for non-invasively determining pulpal blood flow. In vitro studies have shown that laser speckle imaging using a 633 nm HeNe laser can detect blood flow values within the pulpal chambers of teeth. The ability to detect and semi-quantify different flow rates in the dental pulp has been clearly demonstrated. The data show that with higher flow rates, high speckle flow values are given. We currently are performing in vivo measurements with a prototype dental LSI instrument