CURVATURE CORRECTION FOR MODULATED IMAGING

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 约翰·弗兰西奥尼的实验室正在开发用于外科领域的广域成像技术，这将使定量成像成为可能。最终调制成像将被纳入到这种方法中。靶组织的高度在手术野的宽度上可以有几厘米的变化。此外，野外的组织可能会有一些形状/曲率。为了使成像是定量的，我们需要使用从本质上“平坦”手术视野的校正因子。这是一系列体模测量，旨在开发/验证校正活体测量期间观察到的曲面所需的算法。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. John Frangioni's lab is developing wide field imaging technology for use in the surgical field that will enable quantitative imaging. Eventually Modulated Imaging will be incorporated into this approach. There can be several centimeters of variation in height of the target tissue over the width of the surgical field. In addition, tissues in the field are likely to have some shape/curvature. In order for imaging to be quantitative, we need to employ correction factors that will essentially "flatten" the surgical field. This is a series of phantom measurements aimed to develop/validate algorithms needed for correcting curved surfaces observed during in vivo measurements.