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Gastrointestinal Oncology

Gastrointestinal Oncology
胃肠道肿瘤学
批准号:
8300280
负责人:
MAX S. WICHA
金额:
$16.91万
依托单位国家:
美国
项目类别:
财政年份:
2012
资助国家:
美国
项目状态:
已结题
起止时间:
2012-06-01 至 2017-05-31

项目摘要

项目成果

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中文摘要
翻译
胃肠道肿瘤学计划是一个全面的胃肠道癌症研究计划,包括基础研究、临床研究和翻译研究。该计划由来自密歇根大学9个不同系和两所学校的39名成员组成,每年获得900万美元的直接支持,其中包括440万美元的NCI资金。GI的赠款组合包括一笔210万美元的孢子赠款用于研究结直肠癌和胰腺癌,两笔PO1赠款,U01和U19赠款。该计划的重点是发展对人类胃肠道癌症的原因和预防的基础研究,以及应用这些研究成果的转化研究,以改进对胃肠道癌症的早期和准确的诊断、评估和治疗方法以及与健康质量结果相关的问题。胃肠道肿瘤学计划的基础研究捐赠侧重于细胞生长和分化、干细胞和细胞转移的机制。临床研究的重点是新辅助治疗和生物标志物。结果研究集中在医疗质量问题上。在此期间招募的九名新计划成员包括Marwan Fakih、邹卫平、Grace Chen、Chanda Kumar、Marina Pasca Di Magliano、Patrick Hu、Gazala Khan、Theodore Wling和John Carethers。这个节目,它被评为
英文摘要
The Gastrointestinal Oncology Program Is a comprehensive program in gastrointestinal cancer research encompassing basic research, clinical and translational research. The program consists of 39 members from 9 different departments and two schools within the University of Michigan, receiving $9 million in annual direct support, Including $4.4 in NCI funding. The GI grant portfolio includes a $2.1 M SPORE grant to study colorectal and pancreatic cancer, two PO1 grants, U01 and U19 grants. The program is focused on the development of fundamental basic research into the causes and prevention of human gastrointestinal cancers and translational studies applying these research findings to improve the early and accurate diagnosis, evaluation, and therapeutic approaches to gastrointestinal cancer as well as Issues related to health quality outcomes, The basic research alms of the Gastrointestinal Oncology Program focus on mechanisms of cell growth and differentiation, stem cells and cell metastasis. The clinical research focuses on neoadjuvant therapies and biomarkers. The outcome research focuses on health care quality Issues. Nine new program members recruited over this grant period include Drs Marwan Fakih, Weiping Zou, Grace Chen, Chandan Kumar, Marina Pasca Di Magliano, Patrick Hu, Gazala Khan, Theodore Welling, and John Carethers. This program, which was rated as
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Targeting breast cancer stem cells
Targeting breast cancer stem cells
Targeting breast cancer stem cells
Cancer Cell Biology
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