National Biocontainment Laboratories (NBLs) Operations Support

加尔维斯顿国家实验室（GNL）的使命是进行基础和应用研究， 改善自然出现和有目的传播的疾病的预防、诊断和治疗， 传染病GNL提供BSL 4，BSL 3和BSL 2实验室，旨在确保安全 进行这项工作。我们的战略计划是发展基础研究和过渡产品的组合 将完全占据GNL安全壳空间的开发活动，包括实施 我们的每个综合服务支助司都有成本回收战略;但是，我们认识到， 安全和有保障的行动所需的安保、水电和维修等额外费用将 要求补充支持。GNL于2008年11月11日投入使用。截至6月， 2010年，整个GNL已通过CDC和USDA选择代理程序的检查，并批准用于 全面运营。GNL BSL 2和ABSL 3实验室正在积极开展工作，并正朝着满员的方向发展; BSL 3和BSL 3E实验室可使用非Select Agent，我们将很快开始使用Select Agent。我们 预计2010年8月开始在BSL 4实验室运行，最初进行的研究是 到2010年底，需要较低控制和处理BSL 4病原体的病原体。例行计划， 应急和预防性实验室维护以及天气应急计划都在运作， 计划的外部评估。GNL由6个核心和7个服务部门组成 （行政、设施维护和运作、生物安保、环境卫生和生物安全） 法规和要求、法规遵从性和集成支持服务核心; 空气生物学、临床前、检测开发、病理学、昆虫学、成像和免疫学服务 司）。在国家生物防护培训中心的协助下，工作人员的培训正在进行。两种活性 社区咨询小组帮助与当地社区领导人保持强有力的积极对话。 GNL协助德克萨斯州卫生部应对2009年H1N1疫情， 在这一模式的基础上，正式确定各州和全国的应急活动。

The mission ofthe Galveston National Laboratory (GNL) is to conduct basic and applied research designed to improve the prevention, diagnosis and treatment of naturally emerging and purposefully disseminated infectious diseases. The GNL provides BSL4, BSL3 and BSL2 laboratories designed to allow the safe conduct of this work. Our strategic plan is to develop a portfolio of basic research and transiational product development activities that will fully occupy the GNL containment spaces, including implementation of strategies for cost recovery for each of our Integrated Service Support Divisions; however, we realize that the exceptional costs of security, utilities and maintenance required for the safe and secure operations will confinue to demand supplemental support. The GNL was dedicated on November 11, 2008. As of June, 2010, the entire GNL has been inspected by the CDC and USDA Select Agent Programs and approved for full operations. GNL BSL2 and ABSL3 laboratories are active and moving toward full occupancy; the in vitro BSL3 and BSL3E labs are operational with non-Select Agents, and we will soon begin Select Agent use. We anticipate beginning operations in the BSL4 laboratories in August 2010, initially conducting research on pathogens requiring lower containment and handling BSL4 pathogens by the end of 2010. Plans for routine, emergency and preventive laboratory maintenance are operational, as are weather emergency plans and plans for external evaluation of programs. The GNL is organized around 6 Cores and 7 service divisions (Administration, Facilities Maintenance and Operations, Biosecurity, Environmental Health and Biosafety Regulations and Requirements, Regulatory Compliance, and Integrated Support Services Cores; Aerobiology, Preclinical, Assay Development, Pathology, Insectary, Imaging and Immunology service divisions). Staff training is undenway, facilitated by the National Biocontainment Training Center. Two active community advisory groups help to maintain a robust and positive dialogue with local community leaders. The GNL assisted the Texas Department of State Health in response to the 2009 H1N1 epidemic and is building upon that model to formalize state and national emergency response activities.