West Virginia IDEA-CTR

描述（由申请人提供）：西弗吉尼亚临床与转化科学研究所（WVCTSI） IDeA-CTR申请的目标是扩大我们临床和转化研究的基础设施和实践，以达到临床和转化科学奖（CTSA）的竞争水平。为此，2008年成立了西维吉尼亚州和阿巴拉契亚中部地区人口健康和保健研究中心，作为支持研究的组织机构，以满足西维吉尼亚州和阿巴拉契亚中部地区人民的健康和保健需求，并最终消除健康差距。为了实现我们雄心勃勃的目标，WVCTSI，包括西弗吉尼亚大学，查尔斯顿地区医学中心，西弗吉尼亚骨科医学院和西弗吉尼亚联合卫生系统，与阿巴拉契亚转化研究所合作，该研究所由我们的IDeA州合作伙伴和CTSA接受者肯塔基大学建立。WVCTSI将通过追求三个目标来实现其目标：1)将WVCTSI发展成为一个学术中心，并促进针对癌症、心血管中风和肥胖相关疾病的临床和转化研究；2)在WVCTSI合作机构和肯塔基大学、俄亥俄州立大学和印第安纳大学的合作ctsa之间建立跨领域的研究伙伴关系，以提高我们的研究能力；3)利用创新的招聘、培训和指导策略，在每个WVCTSI机构培养临床和转化科学家。这些目标是通过招募和支持临床和转化科学家以及广泛的教育和指导计划来实现的。此外，参与的教师将获得包括生物统计学、临床信息学在内的研究资源，并获得一系列试点资助机制。此外，正在制定在不损害人类受试者保护的情况下简化管理程序和使社区充分参与研究议程的机制。最后，为了确保问责制和质量的提高，我们建立了一个强有力的评估项目。总的来说，WVCTSI已经建立了一个强大的基础设施，以增加校外资助的临床和转化研究人员的数量，并制定了一个经过深思熟虑的计划，以提高未来五年的能力和生产力，使我们在CTSA中具有竞争力。

DESCRIPTION (provided by applicant): The goal of the West Virginia Clinical and Translation Science Institute's (WVCTSI) IDeA-CTR application is to expand our infrastructure for, and practice of, clinical and translational research to a level competitive for a Clinical and Translational Science Award (CTSA). To this end, the WVCTSI was established in 2008 as the organizational home supporting research to address the health and healthcare needs of the people of West Virginia and Central Appalachia, and ultimately to eliminate health disparities. To realize our ambitious goal, the WVCTSI, which includes West Virginia University, Charleston Area Medical Center, West Virginia School of Osteopathic Medicine, and West Virginia United Health Systems, has partnered with the Appalachian Translational Research Institute, which was founded by our IDeA state partner and CTSA recipient the University of Kentucky. The WVCTSI will achieve its goal through pursuit of three aims: 1) Grow the WVCTSI as an academic home and a catalyst for clinical and translational research that targets cancer, cardiovascular-stroke, and obesity related diseases; 2) Establish cross cutting research partnerships among the WVCTSI partnered institutions and collaborating CTSAs at University of Kentucky, Ohio State University, and Indiana University to increase our research capacity; and 3) Utilize innovative recruitment, training, and mentoring strategies to develop clinical and translational scientists at each of the WVCTSI institutions. These aims are addressed through recruitment and support of clinical and translational scientists and a broad educational and mentoring program. In addition, participating faculty are provided with research resources that include biostatistics, clinical informatics, and access to a range of pilot funding mechanisms. Furthermore, mechanisms to streamline regulatory processes without compromising human subject protections and to engage communities fully in the research agenda are being developed. Finally, to ensure accountability and quality improvement, a robust evaluation program has been established. Overall, the WVCTSI has developed a strong infrastructure to increase the number of extramural funded clinical and translational researchers and has a well-considered plan for enhancing capacity and productivity over the next five years, positioning us for competitiveness for a CTSA.