Bioinformatics and Computational Biology Training Program

描述（由申请人提供）：本提案是杜克大学计算生物学和生物信息学（CBB）项目培训补助金申请的重新提交。CBB是一个研究生项目。它招收自己的学生，并授予博士学位。它的使命是教育下一代科学家，他们将在生命科学和定量科学之间的界面工作。CBB为学生提供前两年的支持，之后他们将得到教师的支持。该项目旨在每年招收大约10名新生。这个提议要求十个名额，可以容纳一半的学生。该计划通常需要五年才能完成，它包含了广泛的学术活动，包括三个核心课程和三个研究轮转，所有这些都在第一年进行，必要的系列研讨会，仔细的RCR培训，以及跨学科的指导和监督。该项目得到了一个不同寻常的广泛而又融合良好的教师团队的支持。该学院的研究领域非常广泛，分为六个领域：系统生物学、基因组分析、计算结构生物学、基因组医学、进化基因组学和生物系统的数学和统计建模。学生们为在合作研究小组中工作做好了充分的准备，在那里生物学家和计算科学家共同为解决真正的生物学问题做出智力贡献。CBB正在完成从NIH获得初始资金的第五年。这五年来，杜克大学的计算生物学有了显著的发展，该项目现在有57名教师（24名在定量系，33名在生物系），来自三个学院和一个研究所的15个系。优秀的学生已经被招募到该计划中，自该计划开始以来，已经录取的49名学生中有43名已经完成了博士学位或取得了良好的进展。毕业生表现非常出色，6人在著名机构获得博士后职位，4人在工业领域担任要职。

DESCRIPTION (provided by applicant): This proposal is a resubmission of an application for a training grant for the Duke University Program in Computational Biology and Bioinformatics (CBB). CBB is a graduate program. It admits its own students and grants the PhD. Its mission is to educate the next generation of scientists who will work at the interface between the life sciences and the quantitative sciences. CBB supports students for their first two years, after which they move onto support from the faculty. The program aims to admit around ten new students each year. This proposal requests ten slots, which would support half the students. The program typically takes five years to complete, and it embodies a wide range of academic activities, including three core courses and three research rotations, all taken in the first year, a required seminar series, careful RCR training, and interdisciplinary mentoring and supervision. The program is supported by an unusually broad, but well integrated group of faculty. Research areas of the faculty are quite broad, and are grouped into six areas: Systems Biology, Genome Analysis, Computational Structural Biology, Genomic Medicine, Evolutionary Genomics and Mathematical and Statistical Modeling of Biological Systems. Students emerge well prepared to work in collaborative research groups where biologists and computational scientists make joint intellectual contributions to solving real biological problems. CBB is completing its fifth year of initial funding from the NIH. These five years have seen significant growth of computational biology at Duke University, the program now includes 57 faculty (24 in quantitative departments and 33 in biological ones) from 15 departments in three schools and one Institute. Excellent students have bee recruited into the Program and retention is excellent with 43 of the 49 students that have been admitted since the program began having finished their PhD or making good progress towards their degree. Graduates have done extremely well, 6 have taken postdoctoral positions at prestigious institutions and 4 have taken strong industrial positions.