Improving the surgical outcomes for Barretts-derived oesophageal adenocarcinoma through early detection.

一些严重反流的人会患上巴雷特食道，这会使他们处于罹患癌症的高风险中。患有巴雷特病的患者可以通过常规内窥镜进行监测，以便及早发现癌症，以便通过手术成功地治疗他们。这项工作的目的是利用分子生物标记物识别癌症风险最高的患者。然后，我们将确定使用生物标志物监测Barrett‘s食道患者的成本效益。

Some people with severe reflux develop Barrett's oesophagus, which puts them at high risk of developing cancer. Patients with Barrett's can be monitored by regular endoscopy to detect cancer early enough so that they can be treated successfully with surgery. The aim of this work is to identify patients who are at highest risk of cancer using molecular biomarkers. We will then determine the cost effectiveness of using biomarkers for surveillance of patients with Barrett's oesophagus.