Exposure Core

伯克利/斯坦福大学儿童环境健康将调查空气污染在儿童健康中的作用。 特别是对出生结果、出生缺陷、哮喘、肥胖和免疫系统的影响。 索诺马科技公司的（STI）在研究中的作用将是进行暴露评估，作为 核心曝光中心我们将收集周围的多环芳烃和黑碳空气 弗雷斯诺的污染数据，并对不同时间段的受试者暴露情况进行了精确估计 通过数据分析和建模。科技及创新局的工作包括四项主要任务： SJV的历史空气质量;收集弗雷斯诺现有站点的PAH和黑碳数据;进行 饱和抽样活动;并进行暴露数据管理、分析和建模 研究中的所有暴露数据都将得到质量保证，并汇编成一个共同的数据库，供所有人使用。 investigators.历史和当前的空气质量数据将用于分配历史暴露， 相关的时间段。现时的空气质素及气象资料， 分散模型估计和交通，土地使用，地球物理和人口数据，以发展 每日PAH浓度的时空模型。时空模型的发展将是 与UCB工作人员共同进行。此外，如果有足够的数据证明该方法是合理的，STI将采用微环境 建模技术，以估计研究中受试者的个人暴露水平。STI 我将记录我们的方法和结果，并与UCB工作人员一起准备项目具体文件 科学成果的解释。STI PI Fred Lurmann将参加定期的曝光核心 中心会议。

The Berkeley/Stanford Children's Environmental Health will investigate the role of air pollution in children's health, in particular, effects on birth outcomes, birth defects, asthma, obesity, and the immune system. Sonoma Technology Inc.'s (STI) role in the study will be to perform exposure assessment as part of the Center's Exposure Core. We will collect ambient polycyclic aromatic hydrocarbon and black carbon air pollution data in Fresno and developed refined estimates of the subject's exposure for various time periods of their lives through data analysis and modeling. STI's work consists of four main tasks: characterize historical air quality in the SJV; collect PAH and black carbon data at existing stations in Fresno; conduct saturation sampling campaigns; and conduct exposure data management, analysis, and modeling All exposure data from the study will be quality assured and compiled into a common database for use by all investigators. The historical and current air quality data will be used to assign historical exposures for relevant time periods in the subjects lives. The current air quality and meteorological data will be used with dispersion model estimates and traffic, land-use, geophysical, and demographic data to develop spatiotemporal models of daily PAH concentrations. The development of spatiotemporal models will be conducted jointly with UCB staff. In addition, where sufficient data justify the approach, STI will apply microenvironmental modeling techniques to estimate the personal exposure levels of subjects in the study. STI will document our methods and results, and work with UCB staff on the preparation of project specific papers and interpretation of scientific results. Fred Lurmann, the STI PI, will participate in regular Exposure Core and Center meetings.