CSHL Neurobiology of Drosophila

描述（由申请人提供）：本提案要求支持一个独特的国际会议，即2013年在冷泉港举行的两年一次的果蝇神经生物学会议，这是该系列的第15次会议。对于2013年的版本，组织者将会议的重点重新调整为与NIH神经科学蓝图的核心目标直接相关的主题，特别是NINDS的使命，但也包括NICHD， NIDA， NIA和NIMH的使命。特别地，本次会议将探讨在果蝇黑腹果蝇高度成功的模型系统中取得的最新进展，利用遗传学、分子生物学、细胞生物学、电生理学、成像和行为分析的联合力量，解决与人类健康和疾病直接相关的神经生物学基本问题。会议将包括七个幻灯片环节：i)大脑，行为和进化ii)高阶神经系统功能；iii)神经疾病模型和机制；iv)神经回路和计算；v)突触传递和可塑性；vi)神经发育；七是技术创新。还将举行三次海报会议，介绍从这些领域汲取的额外工作。最后，还有一个全体会议演讲，Benzer讲座，由Larry Zipursky博士主持，他是神经生物学领域的领导者之一他的科学贡献从根本上改变了我们对所有生物体中神经发育的多个方面的理解。经往届与会者投票决定，会议将保持中等规模（430名与会者），并将不设平行会议，以便在这一迅速发展的领域促进讨论、思想和技术交流，并促进新的合作。所有申请者将被鼓励提交摘要，大多数参与者将发表演讲或海报。会议领导人和会议组织者将从会议前几个月提交的最及时、最有趣的摘要中选择演讲者：这将确保所有的演讲都涵盖最新的科学。如果会议被超额认购，每个参与实验室将选出至少一名代表参加会议。该会议一直吸引着来自其职业生涯各个阶段的研究人员，并且在促进年轻研究人员和女性的科学发展方面有着悠久的历史。为了鼓励初级研究人员的参与，一个特别的讲座，埃尔金讲座，由一位自上次会议以来写了最好的博士论文的研究生主持。

DESCRIPTION (provided by applicant): This proposal requests support for a unique international meeting, the biennial Neurobiology of Drosophila conference at Cold Spring Harbor to be held in 2013, the 15th meeting in this series. For the 2013 edition, the organizers have refocused the meeting on topics of direct bearing on the central goals of the NIH Neuroscience Blueprint, in particular the mission of NINDS, but also those of NICHD, NIDA, NIA and NIMH. In particular, this meeting will explore the latest advances that are being made in the highly successful model system the fruit fly Drosophila melanogaster using the combined power of genetics, molecular biology, cell biology, electrophysiology, imaging, and behavioral analysis to address fundamental issues in neurobiology with direct relevance to human health and disease. The meeting will comprise seven slide sessions: i) Brain, Behavior and evolution ii) Higher Order Nervous System Function; iii) Neurological disease models & mechanisms; iv) Neural circuits and computation; v) Synaptic transmission and plasticity; vi) Neural development; and vii) Technological innovations. There will also be three poster sessions, presenting additional work drawn from each of these areas. Finally, there will also be one plenary talk, the Benzer lecture, which will be given by Dr. Larry Zipursky, one of the leaders in the field of neurobiology whose scientific contributions have fundamentally changed our understanding of multiple aspects of neural development in all organisms. By vote of the previous participants, the meeting will remain of moderate size (430 participants) and will have no parallel sessions so as to facilitate discussion, exchange of ideas and techniques, and to promote new collaborations in this rapidly-evolving field. All applicants will be encouraged to submit an abstract and the majority of participants will present a talk or poster. Speakers will be chosen by session leaders and meeting organizers from the most timely and interesting abstracts submitted a few months in advance of the conference: this will ensure that late-breaking science is covered in all of the talks. In the event that the conference is oversubscribed, participants will be chosen to include at least one representative from each participating laboratory. This meeting has always attracted investigators from across many stages of their careers, and has a long history of promoting the scientific development of younger investigators and women. To encourage participation by junior investigators, a special lecture, the Elkin's Lecture, is presented by a graduate student who has written the best Ph.D. thesis since the previous meeting.