Duke CTSA (Composite)

实现CTSA联盟的新NCATS愿景并加速将科学发现转化为 患者、学术卫生和科学系统的成果必须投资、转型和创新，以 优化自身独特优势。我们的愿景与NCATS的愿景一致，即创造一个研究环境 在杜克大学，这通过将发现联系起来，刺激了科学发现从替补席到床边的转换 将科学转化为创新引擎，有效地加速新技术的发展；以及2)整合 学习卫生系统中的临床试验、注册和电子健康记录，其中研究和 实践形成了一个连续体。我们的研究环境将受到科学价值和社会需求的推动， 与我们最新的研究机构框架保持一致，对疾病或专业学科采取不可知的态度 监督和质量，并不断评估学术生产力、效率和成本。要实现 为了实现这些目标，我们将创建一个临床和翻译研究的综合之家，通过提供 基础设施和资源，为各个研究领域的研究人员和受训人员提供服务。我们会提供 基于我们研究人员的共同需求的资源，包括教育、生物统计、生物库、 监管专业知识、道德操守、试点资金和招聘援助。我们还将定制我们的产品，以满足 跨研究社区的专业需求，包括早期翻译、概念验证、基于站点的 研究和基于人群的研究，包括多地点试验、结果、卫生服务、 实施科学和社区参与的研究。整合这些资源将需要一个新的 工具，所有受训者和调查人员的门户，MyResearchHome(@Duke，及其人类对应的， MyResearchTeam@duke。这些工具将为所有临床和转换工具提供单一入口点 杜克大学的研究，无论他们的部门或学校。因此，我们将加强我们的综合之家 结合先进的信息技术和指导的临床和转化性研究 和导航；为我们的所有翻译研究提供公共和专业资源的访问 并在我们的教育和培训计划中培训下一代研究人员。 相关性(请参阅说明)： CTSA将促进翻译研究过程，确保新发现的开发和 更快地进行评估，以高质量、高效率、高安全性和高成本进行临床研究- 有效性。

To fulfill the new NCATS vision for the CTSA Consortium and accelerate scientific discoveries into improved outcomes for patients, academic health and science systems must invest, transform, and innovate to optimize their unique strengths. Our vision, aligned with that of NCATS, is to create a research environment at Duke that stimulates the translation of scientific discovery from bench to bedside by 1) linking discovery science to a creative engine that efficiently accelerates development of new technologies; and 2) integrating clinical trials, registries, and electronic health records in a learning health system where research and practice form a continuum. Our research environment will be driven by scientific merit and societal need, "agnostic" to disease or specialty discipline, aligned with our updated institutional framework for research oversight and quality, and continually evaluated for academic productivity, efficiency, and cost. To achieve these goals, we will create an Integrated Home for clinical and translational research by providing infrastructure and resources to serve investigators and trainees across the research spectrum. We will offer resources based upon common needs among our researchers, including education, biostatistics, biobanking, regulatory expertise, ethics, pilot funding and recruitment assistance. We will also tailor our offerings to specialized needs across research communities that include early translation, proof of concept, site-based research and population based research, which includes multi-site trials, outcomes, health services, implementation science and community engaged research. Integrating these resources will require a new tool, a portal for all trainees and investigators, MyResearchHome(@Duke, and its human counterpart, MyResearchTeam@Duke. These tools will provide a single point of entry for all clinical and translational research at Duke, regardless of their department or school. Thus, we will enhance our Integrated Home for clinical and translational research with a combination of sophisticated information technology and mentoring and navigation; provide access to common and specialized resources for all of our translational research communities and train the next generation of researchers in our educational and training programs. RELEVANCE (See instructions): The CTSA will foster the translational research process, ensuring that new discoveries are developed and evaluated more quickly and that clinical research is done with high quality, efficiency, safety and cost- effectiveness.