Community Clinical Oncology Program Research Base

描述（由申请人提供）：儿童肿瘤组（COG）是世界上最大的儿童癌症研究组织，包括216个儿科癌症项目，其使命是通过科学发现和同情心护理来治愈和预防儿童和青少年癌症。COG是由四个传统儿科合作团体于2000年合并而成。COG社区临床肿瘤学项目（CCOP）研究基地于2002年获得资助，作为治疗和癌症预防和控制CCOP研究基地。COG CCOP研究基地支持19个CCOP和7个少数民族CCOP参与癌症治疗，预防和控制的创新临床和转化研究。社区儿科肿瘤学家和其他卫生专业人员参与COG的研究使命至关重要。CCOPs提供了一个重要的机制，以评估在社区环境中管理的先进治疗，并扩大了协议参与的人口基础。该委员会向社区合作方案/基于少数群体的社区合作方案提供目前的治疗方案，使其能够获得研究药物和专门的中央参考实验室、质量保证基础设施和统计支持，从而促进对在社区环境中接受治疗的年轻人的高质量癌症护理。小组委员会为CCOP人员提供持续培训和支助，并确保所有CCOP在成员资格、应计费用和机构业绩方面保持高质量保证标准。 COG进行临床试验，以确定儿童和青少年癌症的最佳治疗方法，重点是解决儿童癌症患者的独特需求。癌症控制委员会开展研究，重点是识别，预防或改善与治疗相关的后遗症，并改善患有癌症的儿童和青少年及其家庭的生活质量。

DESCRIPTION (provided by applicant): The Children's Oncology Group (COG) is the largest childhood cancer research organization in the world and encompasses 216 pediatric cancer programs with a mission to cure and prevent childhood and adolescent cancer through scientific discovery and compassionate care. The COG was formed from the merger of four legacy pediatric cooperative groups in 2000. The COG Community Clinical Oncology Program (CCOP) Research Base was funded in 2002 as a Treatment and Cancer Prevention and Control CCOP Research Base. The COG CCOP Research Base supports 19 CCOPs and 7 Minority-Based CCOPs for participation on innovative clinical and translational research studies for cancer treatment, prevention and control. The involvement of community-based pediatric oncologists and other health professionals in the research mission of the COG is pivotal. CCOPs provide an important mechanism to evaluate advanced treatments administered in community settings and broaden the population-base for protocol participation. The COG makes available to CCOPs/Minority-Based CCOPs current treatment protocols with access to investigational agents and special centralized reference laboratories, quality assurance infrastructure and statistical support, thus promoting high quality cancer care for young persons treated in community settings. The COG provides continuing training and support for CCOP personnel and ensures that all CCOPs maintain high quality assurance standards for membership, accrual, and institutional performance. COG conducts clinical trials to define optimal treatments for children and adolescents with cancer, with a focus on addressing the unique needs of children afflicted with cancer. The Cancer Control Committee develops studies that focus on identifying, preventing or ameliorating treatment-related sequelae and improving the quality of life for children and adolescents with cancer and their families.