Salmonella serotype distribution in pets presented to veterinary teaching and com

项目摘要 包括狗和猫在内的同伴动物是已知的沙门氏菌宿主。和潜在的来源 通过直接或间接接触传播给人类。伴生动物粪便中的沙门氏菌 可能构成环境污染和人类感染的主要风险因素。潜在风险 宠物容易感染沙门氏菌的因素包括食用受污染的饲料、水和其他 环境水库。宠物主人在与宠物互动时，可能会处理受污染的食物、水、 或浪费，对业主构成风险，并暴露出潜在的公共卫生问题。这是一个稀缺的 检测沙门氏菌流行率的研究。并找出有症状的和 送到兽医诊所的无症状宠物。我们建议进行一项多中心横断面研究 与北卡罗来纳州州立大学兽医学院医院和两家当地兽医合作 同一地区的做法，以确定同伴动物(狗和猫)中沙门氏菌的流行情况 被送去接受治疗。我们将收集有关历史、饲料消耗和其他重要数据的适当数据 来自宠物主人的信息，以帮助这项研究。我们的研究目标如下： 1)确定沙门氏菌的流行是有症状的(N=100)和无症状的(N=100)宠物(狗 被送到我们参与的兽医诊所接受治疗。 2)家养宠物分离的沙门氏菌的血清型鉴定。 3)收集有关病史的重要信息，包括出现症状和消耗的饲料， 帮助确定沙门氏菌病的潜在风险因素。 这项研究收集到的信息将帮助我们实现减轻 家养宠物中的沙门氏菌，并改善公共卫生。

Project Summary Companion animals, including dogs and cats, are known reservoirs of Salmonella spp. and potential sources of transmission for humans through direct or indirect contact. Salmonella shed by companion animals in feces could constitute a major risk factor for environmental contamination and infection of humans. Potential risk factors that predispose pets to Salmonella infection include consumption of contaminated feed, water and other environmental reservoirs. Pet owners, while interacting with their pets, may handle contaminated food, water, or waste, constituting risk to the owners and revealing a potential public health issue. There is a dearth of studies examining the prevalence of Salmonella spp. and identifying potential risk factors in symptomatic and asymptomatic pets presented to veterinary clinics. We propose to conduct a multicenter cross-sectional study in association with our College of Veterinary Medicine Hospital at NC State University, and two local veterinary practices in the same region, to determine the prevalence of Salmonella in companion animals (dogs and cats) presented for treatment. We will collect appropriate data on history, feed consumption, and other important information from pet owners to aid in this study. Our study objectives are as follows: 1) Establish the prevalence of Salmonella is symptomatic (N=100) and asymptomatic (n=100) pets (dogs and cats) that are presented to our participating veterinary clinics for treatment. 2) Determine the serotype of the Salmonella strains isolated from the domestic pets. 3) Collect important information on the case history, including presenting symptoms and feed consumed, to aid in determining the potential risk factors for salmonellosis. The information gathered in this study will help us achieve our long term goal of reducing the burden of Salmonella in domestic pets and improve public health.