Postdoctoral Research Training in Anesthesiology and Critical Care Medicine

描述(由申请人提供)：麻醉学成功地使术中环境成为一个极其安全的地方，这一成就现在被其他专业承认和效仿，但不应该掩盖这样一个事实，即关于整个围手术期经验的重要基本问题仍然没有得到回答。这些问题涉及1)全身麻醉作用的机制，2)围手术期状态的生理学，3)术后精神错乱和认知功能障碍的机制和预防，4)在整个围手术期提供安全性，5)改善长期结果，以及6)急慢性疼痛的治疗。然而，维持将指导麻醉学领域走向未来的科学基础设施需要一个训练有素、积极进取的专业内科医生-科学家的核心，他们致力于追求对麻醉学重要的问题。为了帮助确保麻醉学在科学上有一个稳健的未来，约翰霍普金斯大学麻醉学和重症监护医学系(ACCM)提交了这份申请，以支持麻醉学的博士后研究培训。除了为学员提供支持的重要途径外，预计该计划还将继续改进约翰霍普金斯大学ACCM招募、培训和培养麻醉学专业下一代内科科学家的方法。ACM在提供临床和基础麻醉学研究培训方面有着悠久而富有成效的历史，本培训计划将继续培养和正规化这一培训项目。目前，培训方案支持的优秀受训人员正在取得积极成果。与约翰·霍普金斯大学现有的用于教师发展的大量资源相结合，麻醉学博士后研究培训补助金将继续为培训内科科学家提供一个出色的机会，以扩大麻醉学实践的科学基础。

DESCRIPTION (provided by applicant): Anesthesiology's success in making the intraoperative environment an extremely safe place, an accomplishment now recognized and emulated by other specialties, should not obscure the fact that important fundamental questions about the entire perioperative experience remain unanswered. These questions pertain to 1) the mechanism of general anesthetic action, 2) physiology of the perioperative state, 3) the mechanism and prevention of postoperative delirium and cognitive dysfunction, 4) providing safety throughout the entire perioperative period, 5) improving long-term outcomes, and 6) the treatment of acute and chronic pain. However, maintaining the scientific infrastructure that will guide the field of Anesthesiology into the future requires a core of well-trained and motivated physician-scientists within the specialty who are dedicated to the pursuit of problems important to Anesthesiology. To help ensure a scientifically robust future for Anesthesiology, the Department of Anesthesiology and Critical Care Medicine (ACCM) at the Johns Hopkins University is submitting this application to support Postdoctoral Research Training in Anesthesiology. In addition to providing a critical avenue for the support of Trainees, it is anticipated that this program will continue to refine the approach whereby Johns Hopkins ACCM recruits, trains, and develops the next generation of physician-scientists in the specialty of Anesthesiology. ACCM has a long and productive history of providing training in clinical and basic Anesthesiology research, which this Training Program will continue to cultivate and formalize. Positive results are now being realized with the outstanding Trainees currently supported by the Training Program. Combined with the considerable resources already in place for faculty development at Johns Hopkins University, an Anesthesiology Post Doctoral Research Training Grant will continue to provide an outstanding opportunity for training physician-scientists to extend the scientific foundation for the practice of Anesthesiology.