Training in Host-pathogens interactions

描述（由申请人提供）：我们正在寻求支持，在宿主-病原体相互作用领域培养研究生，为期五年。来自马里兰大学5个学院的17名研究人员，他们的主要研究兴趣与宿主-病原体相互作用有关，他们聚集在一起，在化学与生命科学学院新成立的BISI研究生项目中形成了一个研究集群。结核病、脑膜炎、利什曼病、流感和其他寄生虫感染等病原体引起的传染病的破坏性影响是众所周知的，从世界卫生的角度来看，了解微生物发病机制的努力很容易得到证明。微生物病原体的重要性远远超出了它们引起的疾病，因为研究它们的发病机制将导致免疫学和细胞生物学的新见解。因此，这是培养研究生的一个极好的领域。本培训计划寻求一个独特的培训计划的支持，该计划将使学生沉浸在跨学科研究中，努力将基因组学，免疫学和微生物发病机制的进展与我们对宿主-病原体相互作用的快速扩展的理解结合起来。该计划的目标是培养宿主-病原体相互作用的基本细胞和分子生物学的研究生，并着眼于开发改善健康的转化方法。

DESCRIPTION (provided by applicant): We are seeking support to train graduate students over a five year period in the area of host-pathogen interactions. Seventeen investigators in 5 colleges at the University of Maryland whose primary research interest pertains to host-pathogen interactions have come together to form a research cluster in the newly- formed BISI graduate program in the College of Chemical and Life Sciences. The devastating effects of infectious diseases caused by pathogens such as tuberculosis, meningitis, leishmaniasis, influenza and other parasitic infections, etc. are well known, and efforts to understand the mechanisms of microbial pathogenesis are easily justified from a world health perspective. The importance of microbial pathogens extends well beyond the diseases they cause, because studying their pathogenesis will lead to new insights in immunology and cellular biology. Thus, this is an excellent area for graduate student training. This training proposal seeks support for a unique training program that will immerse students in interdisciplinary research, striving to integrate advances in genomics, immunology, and microbial pathogenesis with our rapidly expanding understanding of host-pathogen interactions. The goal of this program is to train graduate students in basic cell and molecular biology of host-pathogen interactions, with an eye to developing translational approaches to improve health. RELEVANCE (See instructions): Pathogens infect nearly all life forms and many have the potential to cause world-wide pandemics. This training proposal seeks support to train predoctoral students to meet the research challenges that these diseases are likely to create. The diverse faculty will bring a variety of expertise to bear on problems that are common to studying host-pathogen interactions. This program includes developing strategies to protect humans and animals to improve the quality of people's lives.